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General Medication Fact Sheet for Pamelor
| Field | Information |
|---|---|
| Medication Name | Pamelor |
| Generic Name | Nortriptyline |
| Boxed/Label Warning | Antidepressants may increase the risk of suicidal thoughts and behavior in children, adolescents, and young adults. |
| Purpose | Treatment of depression |
| Mechanism of Action | Inhibits the reuptake of norepinephrine and serotonin in the brain, increasing their levels and improving mood. |
| Dosage Forms | Oral capsules, oral solution |
| Available Strengths | 10 mg, 25 mg, 50 mg, 75 mg |
| Dosage Frequency | Typically 1 to 4 times daily, or as directed by a healthcare provider. |
| Common Side Effects | Dry mouth, constipation, blurred vision, drowsiness, dizziness |
| Serious Side Effects | Changes in heart rhythm (arrhythmias), seizures, confusion, mania, glaucoma |
| Drug Interactions | MAO inhibitors, SSRIs, SNRIs, other antidepressants, certain antihistamines, cimetidine, quinidine |
| Important Notes | Avoid alcohol while taking this medication; may cause drowsiness; use caution when driving or operating machinery; consult a doctor if you have heart problems or glaucoma. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Amitriptyline, Imipramine, Desipramine, Sertraline |
Pamelor Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Amitriptyline (Elavil) | Tricyclic antidepressant; inhibits reuptake of serotonin and norepinephrine. | Another tricyclic antidepressant with similar effects. |
| Imipramine (Tofranil) | Tricyclic antidepressant; inhibits reuptake of serotonin and norepinephrine. | Another tricyclic antidepressant option. |
| Desipramine (Norpramin) | Tricyclic antidepressant; primarily inhibits norepinephrine reuptake. | More selective for norepinephrine reuptake. |
| Sertraline (Zoloft) | Selective serotonin reuptake inhibitor (SSRI) | A different class of antidepressant that primarily affects serotonin. |
Pamelor Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Dry mouth | Changes in heart rhythm (arrhythmias) |
| Constipation | Seizures |
| Blurred vision | Confusion |
| Drowsiness | Mania |
| Dizziness | Glaucoma |
Pamelor Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Depression (Adults) | 25 mg once or twice daily | 25-100 mg daily, divided into multiple doses | Dosage may be adjusted based on individual response and tolerance. |
| Depression (Elderly) | 10-25 mg daily | 30-50 mg daily | Start with a lower dose due to increased sensitivity to side effects. |
Pamelor Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $15 |
| Without Insurance (U.S.) | $40 |
| From CPS | $44.95 |
