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Penlac Nail Lacquer (Ciclopirox)
| Ciclopirox (Generic) Ciclopirox | ||||||
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Shipped from Canada | ||||||
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General Medication Fact Sheet for Penlac Nail Lacquer
| Field | Information |
|---|---|
| Medication Name | Penlac Nail Lacquer |
| Generic Name | Ciclopirox |
| Purpose | Antifungal medication used to treat fungal infections of the fingernails and toenails. |
| Mechanism of Action | Inhibits the growth of fungi by disrupting the synthesis of DNA, RNA, and proteins within the fungal cell. |
| Dosage Forms | Topical solution (nail lacquer) |
| Available Strengths | 8% |
| Dosage Frequency | Apply to affected nails once daily, preferably at bedtime. |
| Common Side Effects | Redness, itching, burning, or stinging at the application site; nail shape changes; discoloration. |
| Serious Side Effects | Severe allergic reactions (rare); blistering, peeling, or swelling at the application site. |
| Drug Interactions | No known significant drug interactions with topical ciclopirox. |
| Important Notes | For external use on nails only. Avoid contact with eyes and mucous membranes. Use regularly for the full treatment duration. May take several months to see improvement. Consult a doctor if the condition worsens or does not improve. |
| Storage | Store at room temperature away from heat and direct light. Keep the bottle tightly closed. |
| Missed Dose | Apply as soon as you remember. If it is almost time for your next application, skip the missed one and continue with your regular schedule. Do not apply a double dose. |
| Alternatives | Terbinafine (Lamisil), Itraconazole (Sporanox), Griseofulvin, Topical antifungals (e.g., efinaconazole, tavaborole) |
Penlac Nail Lacquer Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Terbinafine (Lamisil) | Inhibits squalene epoxidase, a key enzyme in fungal sterol biosynthesis. | Oral medication; effective for many nail infections but has potential liver side effects. |
| Itraconazole (Sporanox) | Inhibits the synthesis of ergosterol, an essential component of fungal cell membranes. | Oral medication; also effective but can have drug interactions. |
| Griseofulvin | Inhibits fungal cell mitosis by interfering with the microtubule structure. | Oral medication; older treatment option with various side effects. |
| Efinaconazole (Jublia) | Inhibits fungal lanosterol 14-alpha demethylase. | Topical solution; newer option, applied directly to the nail. |
| Tavaborole (Kerydin) | Inhibits fungal leucyl-tRNA synthetase. | Topical solution; another newer topical option. |
Penlac Nail Lacquer Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Redness at application site | Severe allergic reaction (rash, itching, swelling, difficulty breathing) |
| Itching at application site | Blistering at application site |
| Burning sensation at application site | Peeling at application site |
| Stinging at application site | Swelling at application site |
Penlac Nail Lacquer Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Onychomycosis (Fingernail) | Apply a thin layer to all affected nails | Apply a thin layer to all affected nails daily | Apply once daily, preferably at bedtime, to all affected nails. Remove loose nail material with clippers or nail file as needed. Apply over the entire nail plate. |
| Onychomycosis (Toenail) | Apply a thin layer to all affected nails | Apply a thin layer to all affected nails daily | Apply once daily, preferably at bedtime, to all affected nails. Remove loose nail material with clippers or nail file as needed. Apply over the entire nail plate. |
Penlac Nail Lacquer Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $80 |
| Without Insurance (U.S.) | $150 – $250 |
| From CPS | $51.95 |
