Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
Pennsaid (Diclofenac)
| Diclofenac Topical Solution (Generic) Diclofenac Sodium | ||||||
|
Shipped from Canada | ||||||
| | ||||||
| Select product strength & quantity:
Who is the product for? YouOtherAdd Family Member/PetYou must be logged in to add additional members to the order. Don't have an account? or Add Family Member/PetSign inTo continue, please enter your email address and password that you use for your account. | ||||||
General Medication Fact Sheet for Pennsaid
| Field | Information |
|---|---|
| Medication Name | Pennsaid |
| Generic Name | Diclofenac Sodium |
| Purpose | Non-steroidal anti-inflammatory drug (NSAID) used to relieve pain of osteoarthritis in the knees. |
| Mechanism of Action | Inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin synthesis, which reduces inflammation and pain. |
| Dosage Forms | Topical solution |
| Available Strengths | 2% |
| Dosage Frequency | Apply to affected knee(s) twice daily, as directed by a healthcare provider. |
| Common Side Effects | Application site reactions (dryness, redness, itching), headache. |
| Serious Side Effects | Allergic reactions (rash, itching, swelling, difficulty breathing), signs of stomach bleeding (bloody or black stools, vomiting blood), liver problems. |
| Drug Interactions | Other NSAIDs, anticoagulants (e.g., warfarin), aspirin. |
| Important Notes | Avoid contact with eyes and mucous membranes. Do not apply to open wounds or infected areas. Consult a doctor if you have heart, liver, or kidney problems. |
| Storage | Store at room temperature away from moisture and light. Keep tightly closed. |
| Missed Dose | Apply as soon as you remember; if it’s almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. |
| Alternatives | Diclofenac Gel (Voltaren), Ibuprofen, Naproxen, Celecoxib |
Pennsaid Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Diclofenac Gel (Voltaren) | Non-selective COX inhibitor | Topical NSAID for localized pain relief. |
| Ibuprofen (Advil, Motrin) | Non-selective COX inhibitor | Oral NSAID for pain relief. |
| Naproxen (Aleve) | Non-selective COX inhibitor | Oral NSAID with longer-lasting pain relief compared to ibuprofen. |
| Celecoxib (Celebrex) | Selective COX-2 inhibitor | Oral NSAID that may have a lower risk of gastrointestinal side effects compared to non-selective NSAIDs. |
Pennsaid Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Application site reactions (dryness, redness, itching) | Allergic reactions (rash, itching, swelling, difficulty breathing) |
| Headache | Signs of stomach bleeding (bloody or black stools, vomiting blood) |
| Skin rash | Liver problems (yellowing of skin or eyes, dark urine) |
| Dry skin | Kidney problems (changes in urination) |
Pennsaid Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Osteoarthritis Knee Pain | 40 drops per knee | 40 drops per knee twice daily | Apply to clean, dry skin. Do not bandage. Allow to dry before covering with clothing. |
Pennsaid Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $100 |
| Without Insurance (U.S.) | $1,200 – $2,800 |
| From CPS | $69.95 |
