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General Medication Fact Sheet for Piroxicam
| Field | Information |
|---|---|
| Generic Name | Piroxicam |
| Brand Name Versions | Feldene |
| Boxed/Label Warning | NSAIDs may increase the risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal. NSAIDs also increase the risk of serious gastrointestinal (GI) adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. |
| Purpose | Non-steroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation |
| Mechanism of Action | Inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin synthesis |
| Dosage Forms | Oral capsules |
| Available Strengths | 10 mg, 20 mg |
| Dosage Frequency | Typically once daily, or as directed by a healthcare provider |
| Common Side Effects | Abdominal pain, nausea, diarrhea, indigestion, headache |
| Serious Side Effects | Gastrointestinal bleeding, liver problems, kidney problems, allergic reactions, heart problems |
| Drug Interactions | Other NSAIDs, anticoagulants (e.g., warfarin), aspirin, certain antidepressants (SSRIs), ACE inhibitors, diuretics, lithium |
| Important Notes | Take with food to minimize stomach upset; consult a doctor if you have heart, liver, or kidney problems. Use the lowest effective dose for the shortest duration. |
| Storage | Store at room temperature away from moisture and light |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Ibuprofen, Naproxen, Celecoxib, Diclofenac, Meloxicam |
Piroxicam Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Ibuprofen (Advil, Motrin) | Non-selective COX inhibitor | Commonly used for mild to moderate pain relief. |
| Naproxen (Aleve) | Non-selective COX inhibitor | Longer-lasting pain relief compared to ibuprofen. |
| Celecoxib (Celebrex) | Selective COX-2 inhibitor | May have a lower risk of gastrointestinal side effects compared to non-selective NSAIDs. |
| Diclofenac (Voltaren) | Non-selective COX inhibitor | Available in topical and oral forms. |
| Meloxicam (Mobic) | Preferentially inhibits COX-2 | Once-daily NSAID for osteoarthritis and rheumatoid arthritis. |
Piroxicam Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Abdominal pain | Gastrointestinal bleeding |
| Nausea | Liver problems |
| Diarrhea | Kidney problems |
| Indigestion | Allergic reactions (rash, itching, swelling, difficulty breathing) |
| Headache | Heart problems (increased risk of heart attack or stroke) |
| Dizziness | High blood pressure |
Piroxicam Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Osteoarthritis | 20 mg | 20 mg once daily | Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals. |
| Rheumatoid Arthritis | 20 mg | 20 mg once daily | Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals. |
| Ankylosing Spondylitis | 20 mg | 20 mg once daily | Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals. |
Piroxicam Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $20 |
| Without Insurance (U.S.) | $75 |
| From CPS | $27 |
