Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
Pramipexole (Generic)
| Mirapex Pramipexole Dihydrochloride | ||||||
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Shipped from Canada | ||||||
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| Select product strength & quantity:
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General Medication Fact Sheet for Pramipexole
| Field | Information |
|---|---|
| Generic Name | Pramipexole |
| Brand Name Versions | Mirapex |
| Purpose | Treats Parkinson’s disease and restless legs syndrome (RLS) |
| Mechanism of Action | Dopamine receptor agonist; stimulates dopamine receptors in the brain |
| Dosage Forms | Oral tablets |
| Available Strengths | 0.125 mg, 0.25 mg, 0.5 mg, 0.75 mg, 1 mg, 1.5 mg, 3 mg, 4.5 mg |
| Dosage Frequency | Usually taken three times daily for Parkinson’s disease; once daily for RLS, as directed by a healthcare provider |
| Common Side Effects | Nausea, dizziness, drowsiness, insomnia, constipation, dry mouth |
| Serious Side Effects | Hallucinations, impulse control problems (e.g., compulsive gambling, hypersexuality), sudden sleep onset, orthostatic hypotension |
| Drug Interactions | Dopamine antagonists (e.g., antipsychotics), cimetidine, metoclopramide |
| Important Notes | May cause drowsiness; avoid driving or operating heavy machinery until you know how this medication affects you. Report any unusual behaviors or urges to your doctor. |
| Storage | Store at room temperature away from moisture and light |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Levodopa/Carbidopa, Ropinirole, Rotigotine, Apomorphine |
Pramipexole Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Levodopa/Carbidopa (Sinemet) | Levodopa is converted to dopamine in the brain; carbidopa prevents levodopa breakdown | A standard treatment for Parkinson’s disease. |
| Ropinirole (Requip) | Dopamine receptor agonist | Another dopamine agonist used for Parkinson’s and RLS. |
| Rotigotine (Neupro) | Dopamine receptor agonist | Available as a transdermal patch; used for Parkinson’s and RLS. |
| Apomorphine (Apokyn) | Dopamine receptor agonist | Used as a rescue medication for “off” episodes in Parkinson’s disease. |
Pramipexole Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Nausea | Hallucinations |
| Dizziness | Impulse control problems (e.g., compulsive gambling, hypersexuality) |
| Drowsiness | Sudden sleep onset |
| Insomnia | Orthostatic hypotension |
| Constipation | Dyskinesia (involuntary movements) |
| Dry mouth | Peripheral edema (swelling in the extremities) |
Pramipexole Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Parkinson’s Disease | 0.125 mg three times daily | Gradually increased every 5-7 days, based on response and tolerance, to a maximum of 4.5 mg/day | Take with or without food. Dosage adjustments are common. |
| Restless Legs Syndrome (RLS) | 0.125 mg once daily | May be increased every 4-7 days, based on response and tolerance, usually taken 1-3 hours before bedtime | Take with or without food. Dosage adjustments are common. |
Pramipexole Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $10 |
| Without Insurance (U.S.) | $40 |
| From CPS | $24 |
