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Prednisone (Generic)
| Prednisone (Generic) Prednisone | ||||||
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Shipped from Mauritius | ||||||
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General Medication Fact Sheet for Prednisone
| Field | Information |
|---|---|
| Generic Name | Prednisone |
| Brand Name Versions | Deltasone, Rayos |
| Purpose | Corticosteroid used to suppress the immune system and reduce inflammation in various conditions. |
| Mechanism of Action | Binds to glucocorticoid receptors, modifying gene transcription and reducing inflammation. |
| Dosage Forms | Oral tablets, oral solution |
| Available Strengths | 1 mg, 2.5 mg, 5 mg, 10 mg, 20 mg, 50 mg |
| Dosage Frequency | Once daily, multiple times daily, or alternate-day dosing, as directed by a healthcare provider. |
| Common Side Effects | Increased appetite, weight gain, mood changes, insomnia, fluid retention. |
| Serious Side Effects | High blood sugar, increased risk of infection, osteoporosis, adrenal suppression, glaucoma. |
| Drug Interactions | NSAIDs, diuretics, anticoagulants (e.g., warfarin), certain antibiotics, diabetes medications. |
| Important Notes | Do not stop taking Prednisone suddenly without consulting your doctor; long-term use can lead to adrenal suppression. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Methylprednisolone, Dexamethasone, Hydrocortisone, Prednisolone. |
Prednisone Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Methylprednisolone (Medrol) | Binds to glucocorticoid receptors, modifying gene transcription. | A synthetic glucocorticoid with similar uses and side effects as prednisone. |
| Dexamethasone (Decadron) | Binds to glucocorticoid receptors, modifying gene transcription. | A potent corticosteroid, often used for short-term treatment due to its longer half-life. |
| Hydrocortisone (Cortef) | Binds to glucocorticoid receptors, modifying gene transcription. | A milder corticosteroid, often used for skin conditions or adrenal insufficiency. |
| Prednisolone (Orapred, Prelone) | Binds to glucocorticoid receptors, modifying gene transcription. | Active metabolite of prednisone, may be preferred in patients with liver dysfunction. |
Prednisone Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Increased appetite | High blood sugar (hyperglycemia) |
| Weight gain | Increased risk of infection |
| Mood changes (irritability, anxiety) | Osteoporosis (bone thinning) |
| Insomnia | Adrenal suppression |
| Fluid retention (swelling) | Glaucoma (increased eye pressure) |
| Acne | Cataracts |
| Thinning skin | Muscle weakness |
Prednisone Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Asthma | 5-60 mg daily | Lowest effective dose | Take with food to reduce stomach upset. |
| Rheumatoid Arthritis | 5-10 mg daily | Lowest effective dose | May be taken as a single dose in the morning. |
| Allergic Reactions | 5-60 mg daily | Tapering dose over several days | Dosage and duration depend on the severity of the reaction. |
| Ulcerative Colitis | 40-60 mg daily | Tapering dose over several weeks | Dosage depends on disease severity. |
| Adrenal Insufficiency | 5-7.5 mg daily | Divided doses | Mimics natural cortisol production. |
