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General Medication Fact Sheet for Previcox
| Field | Information |
|---|---|
| Medication Name | Previcox |
| Generic Name | Firocoxib |
| Purpose | Non-steroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation in dogs |
| Mechanism of Action | Inhibits cyclooxygenase-2 (COX-2) enzyme, reducing prostaglandin synthesis, which mediates pain and inflammation |
| Dosage Forms | Chewable tablets |
| Available Strengths | 57 mg, 227 mg |
| Dosage Frequency | Once daily, as prescribed by a veterinarian |
| Common Side Effects | Loss of appetite, vomiting, diarrhea, increased thirst, increased urination, lethargy |
| Serious Side Effects | Gastrointestinal ulceration, liver damage, kidney damage, jaundice, seizures |
| Drug Interactions | Other NSAIDs, corticosteroids (e.g., prednisone), anticoagulants (e.g., warfarin) |
| Important Notes | Use with caution in dogs with pre-existing kidney, liver, or heart disease; not for use in cats or humans; consult a veterinarian if side effects develop |
| Storage | Store at room temperature away from moisture and light |
| Missed Dose | Give the missed dose as soon as you remember, unless it is almost time for the next dose. Do not double the dose. |
| Alternatives | Deramaxx (deracoxib), Rimadyl (carprofen), Meloxicam |
Previcox Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Deramaxx (deracoxib) | Selective COX-2 inhibitor | Another COX-2 selective NSAID for pain and inflammation in dogs. |
| Rimadyl (carprofen) | COX-2 preferential inhibitor | A commonly used NSAID for pain relief in dogs, with some COX-1 activity. |
| Meloxicam | COX-2 preferential inhibitor | Can be used as an alternative, but should be used with caution and under veterinary guidance. |
Previcox Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Loss of appetite | Gastrointestinal ulceration (black, tarry stools; vomiting blood) |
| Vomiting | Liver damage (jaundice – yellowing of the skin and eyes) |
| Diarrhea | Kidney damage (increased thirst and urination, changes in urine output) |
| Increased thirst | Seizures |
| Increased urination | Allergic reaction (facial swelling, hives, difficulty breathing) |
Previcox Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Osteoarthritis pain | 5 mg/kg (2.3 mg/lb) | 5 mg/kg (2.3 mg/lb) once daily | Administer orally, with or without food. Give as directed by veterinarian. |
| Post-operative pain | 5 mg/kg (2.3 mg/lb) | 5 mg/kg (2.3 mg/lb) once daily | Administer orally, with or without food. Give as directed by veterinarian. |
