Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
General Medication Fact Sheet for Prezcobix
| Field | Information |
|---|---|
| Medication Name | Prezcobix |
| Generic Name | Darunavir/Cobicistat |
| Purpose | Antiretroviral medication used to treat HIV-1 infection |
| Mechanism of Action | Darunavir inhibits HIV-1 protease, preventing viral replication. Cobicistat inhibits CYP3A enzymes, increasing darunavir levels. |
| Dosage Forms | Oral tablets |
| Available Strengths | 800 mg darunavir/150 mg cobicistat |
| Dosage Frequency | Once daily |
| Common Side Effects | Diarrhea, nausea, fatigue, headache |
| Serious Side Effects | Severe skin reactions (e.g., Stevens-Johnson syndrome), liver problems, new or worsening kidney problems, increased cholesterol and triglyceride levels |
| Drug Interactions | Many potential interactions; including CYP3A inhibitors/inducers, antiarrhythmics, anticoagulants, anticonvulsants, antifungals, immunosuppressants, and hormonal contraceptives. Consult a healthcare provider or pharmacist. |
| Important Notes | Take with food. Do not miss doses. Requires consistent use to prevent resistance. Regular monitoring of liver function, kidney function, and lipid levels is necessary. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember; if it is almost time for your next dose, skip the missed dose and take your next dose at the regular time. Do not double the dose. |
| Alternatives | Darunavir (Prezista), Atazanavir (Reyataz), Ritonavir (Norvir), Elvitegravir/Cobicistat/Emtricitabine/Tenofovir alafenamide (Genvoya) |
Prezcobix Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Darunavir (Prezista) | HIV-1 protease inhibitor | Must be taken with Ritonavir or cobicistat to boost levels. |
| Atazanavir (Reyataz) | HIV-1 protease inhibitor | Must be taken with Ritonavir or cobicistat to boost levels. |
| Ritonavir (Norvir) | CYP3A inhibitor, protease inhibitor | Used as a boosting agent with other protease inhibitors. |
| Elvitegravir/Cobicistat/Emtricitabine/Tenofovir alafenamide | Integrase inhibitor, CYP3A inhibitor, NRTI | A complete single-tablet regimen for HIV. |
Prezcobix Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Diarrhea | Severe skin reactions (e.g., Stevens-Johnson syndrome) |
| Nausea | Liver problems |
| Fatigue | New or worsening kidney problems |
| Headache | Increased cholesterol and triglyceride levels |
| Rash | Changes in body fat distribution |
Prezcobix Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| HIV-1 Infection | N/A | 1 tablet (800 mg darunavir/150 mg cobicistat) once daily | Take with food. Consult with a healthcare provider. |
Prezcobix Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $300 |
| Without Insurance (U.S.) | $1,400 |
| From Canada | $870 |
