Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
General Medication Fact Sheet for Proglycem
| Field | Information |
|---|---|
| Medication Name | Proglycem |
| Generic Name | Diazoxide |
| Boxed/Label Warning | Fluid retention can occur, sometimes leading to congestive heart failure, particularly in patients with preexisting cardiac issues. Monitor patients for signs of fluid overload. |
| Purpose | Treats hypoglycemia (low blood sugar) caused by certain medical conditions. |
| Mechanism of Action | Inhibits insulin secretion from the pancreas and causes hyperglycemia (elevated blood sugar). It also has a direct effect of increasing blood glucose levels. |
| Dosage Forms | Oral suspension, Capsule |
| Available Strengths | 50 mg capsule, 50 mg/mL suspension |
| Dosage Frequency | Typically two to three times daily, or as directed by a healthcare provider. |
| Common Side Effects | Sodium and fluid retention, nausea, vomiting, loss of appetite, rapid heart rate. |
| Serious Side Effects | Congestive heart failure, pulmonary hypertension, severe hyperglycemia, ketoacidosis, decreased platelet count (thrombocytopenia), neutropenia. |
| Drug Interactions | Thiazide diuretics, phenytoin, warfarin, other antihypertensive medications. |
| Important Notes | Monitor blood glucose levels regularly. May cause sodium and fluid retention, which can lead to heart failure. Use with caution in patients with impaired renal function. |
| Storage | Store at room temperature away from moisture and light. Keep the bottle tightly closed and protect from freezing. |
| Missed Dose | Take as soon as you remember, unless it is almost time for your next dose. Do not double the dose. |
| Alternatives | Octreotide, Lanreotide, Everolimus. |
Proglycem Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Octreotide | Somatostatin analog that inhibits the release of growth hormone, glucagon, and insulin. | Used for hypoglycemia caused by sulfonylurea overdose or nesidioblastosis. Injected subcutaneously. |
| Lanreotide | Long-acting somatostatin analog, similar to Octreotide. | Used to manage endocrine tumors. Injected intramuscularly. |
| Everolimus | mTOR inhibitor; inhibits cell growth and proliferation. | Used in the treatment of certain tumors and can indirectly help manage hypoglycemia in specific cases. |
Proglycem Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Sodium and fluid retention | Congestive heart failure |
| Nausea | Pulmonary hypertension |
| Vomiting | Severe hyperglycemia |
| Loss of appetite | Ketoacidosis |
| Rapid heart rate | Decreased platelet count (thrombocytopenia) |
| Hyperuricemia (high uric acid levels) | Neutropenia |
Proglycem Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Hypoglycemia (Infants and Children) | 3-8 mg/kg/day divided into two or three doses | Adjust based on blood glucose response; usual range 3-8 mg/kg/day divided into two or three doses | Give orally with a dropper or syringe to ensure accurate dosing. Monitor blood glucose levels frequently. |
| Hypoglycemia (Adults) | 3 mg/kg/day divided into two or three doses | Adjust based on blood glucose response; usual range 3-8 mg/kg/day divided into two or three doses | Give orally; Monitor blood glucose levels frequently. Divide dosage evenly throughout the day. |
Proglycem Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $125 |
| Without Insurance (U.S.) | $500 |
| From CPS | $336 |
