Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
Propafenone (Generic)
| Arythmol Propafenone Hydrochloride | ||||||
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Shipped from Canada | ||||||
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| Arythmol Propafenone Hydrochloride | ||||||
Shipped from United Kingdom | ||||||
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| Rythmol SR Propafenone | ||||||
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Shipped from Canada | ||||||
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General Medication Fact Sheet for Propafenone
| Field | Information |
|---|---|
| Generic Name | Propafenone |
| Brand Name Versions | Rythmol, Rythmol SR |
| Boxed/Label Warning | Increased risk of mortality or non-fatal cardiac arrest in patients with structural heart disease. |
| Purpose | Antiarrhythmic medication used to treat and prevent certain types of irregular heartbeats. |
| Mechanism of Action | Blocks sodium channels in the heart, slowing the conduction of electrical impulses. |
| Dosage Forms | Oral tablets, Extended-release capsules |
| Available Strengths | 150 mg, 225 mg, 300 mg |
| Dosage Frequency | Typically two or three times daily, or as directed by a healthcare provider. |
| Common Side Effects | Dizziness, nausea, vomiting, constipation, unusual taste in mouth. |
| Serious Side Effects | New or worsened arrhythmias, chest pain, shortness of breath, heart failure, liver problems. |
| Drug Interactions | Digoxin, warfarin, beta-blockers, certain antidepressants (SSRIs), CYP2D6 inhibitors. |
| Important Notes | Regular monitoring of heart function is necessary; use caution in patients with structural heart disease or heart failure. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember unless it is almost time for your next dose. Do not double the dose. |
| Alternatives | Amiodarone, Sotalol, Flecainide, Dronedarone |
Propafenone Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Amiodarone (Pacerone, Cordarone) | Potassium, sodium, and calcium channel blocker; beta-adrenergic blocker | Broad-spectrum antiarrhythmic with a long half-life; can have significant side effects. |
| Sotalol (Betapace) | Beta-adrenergic blocker with potassium channel blocking activity | Used for ventricular and supraventricular arrhythmias; can prolong QT interval. |
| Flecainide (Tambocor) | Sodium channel blocker | Similar mechanism to propafenone; increased risk of mortality in patients with structural heart disease. |
| Dronedarone (Multaq) | Potassium, sodium, and calcium channel blocker; beta-adrenergic blocker | Analog of Amiodarone, with a shorter half-life and fewer side effects. |
Propafenone Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Dizziness | New or worsened arrhythmias |
| Nausea | Chest pain |
| Vomiting | Shortness of breath |
| Constipation | Heart failure |
| Unusual taste in mouth | Liver problems |
Propafenone Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Paroxysmal Supraventricular Tachycardia (PSVT) | 150 mg every 8 hours | 150-300 mg every 8 hours | May be increased at a minimum of 3-4 day intervals. |
| Atrial Fibrillation | 150 mg every 8 hours | 150-300 mg every 8 hours | May be increased at a minimum of 3-4 day intervals. |
| Ventricular Arrhythmias | 150 mg every 8 hours | 150-300 mg every 8 hours | Hospitalization recommended when initiating therapy. |
