Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
Protonix (Pantoprazole Sodium)
| Pantoprazole (Generic) Pantoprazole (Pantoprazole Sodium) | ||||||
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Shipped from Canada | ||||||
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| Pantoprazole (Generic) Pantoprazole (Pantoprazole Sodium) | ||||||
Shipped from United Kingdom | ||||||
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| Pantoprazole DR (Generic) Pantoprazole (Pantoprazole Sodium) | ||||||
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Shipped from Canada | ||||||
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| Pantoprazole DR (Generic) Pantoprazole (Pantoprazole Sodium) | ||||||
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Shipped from Mauritius | ||||||
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| Pantoprazole IV Vial (Generic) Pantoprazole | ||||||
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Shipped from Canada | ||||||
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General Medication Fact Sheet for Protonix
| Field | Information |
|---|---|
| Medication Name | Protonix |
| Generic Name | Pantoprazole |
| Purpose | Reduces stomach acid production to treat conditions like GERD, erosive esophagitis, and Zollinger-Ellison syndrome. |
| Mechanism of Action | Proton pump inhibitor (PPI); blocks the H+/K+-ATPase enzyme system (the proton pump) in gastric parietal cells. |
| Dosage Forms | Oral tablets, IV |
| Available Strengths | 20 mg, 40 mg |
| Dosage Frequency | Usually once daily, may be twice daily in some conditions, as directed by a healthcare provider. |
| Common Side Effects | Headache, diarrhea, nausea, abdominal pain, flatulence, dizziness. |
| Serious Side Effects | Severe allergic reactions, kidney problems, low magnesium levels, bone fractures, C. difficile-associated diarrhea. |
| Drug Interactions | Warfarin, methotrexate, clopidogrel, digoxin, certain antifungals (e.g., ketoconazole), HIV medications (e.g., atazanavir). |
| Important Notes | Take 30-60 minutes before a meal. Long-term use may increase the risk of certain side effects. Consult a doctor if symptoms worsen or do not improve. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember, unless it is almost time for your next dose. Do not double the dose. |
| Alternatives | Omeprazole (Prilosec), Esomeprazole (Nexium), Lansoprazole (Prevacid), Famotidine (Pepcid). |
Protonix Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Omeprazole (Prilosec) | Proton pump inhibitor (PPI) | Available over-the-counter and by prescription. |
| Esomeprazole (Nexium) | Proton pump inhibitor (PPI) | Similar to Omeprazole but may have slightly different pharmacokinetic properties. |
| Lansoprazole (Prevacid) | Proton pump inhibitor (PPI) | Available over-the-counter and by prescription. |
| Famotidine (Pepcid) | H2 receptor antagonist | Reduces stomach acid production, but generally less potent than PPIs. |
Protonix Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Headache | Severe allergic reactions (rash, itching, swelling, difficulty breathing) |
| Diarrhea | Kidney problems |
| Nausea | Low magnesium levels (muscle spasms, irregular heartbeat, seizures) |
| Abdominal pain | Bone fractures (especially hip, wrist, or spine with long-term use) |
| Flatulence | C. difficile-associated diarrhea (watery stool, abdominal pain, fever) |
| Dizziness | Vitamin B12 deficiency (with long-term use) |
Protonix Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Erosive Esophagitis | 40 mg once daily | 40 mg once daily for up to 8 weeks; may continue for another 8 weeks if not healed. | Take 30-60 minutes before a meal. |
| GERD | 40 mg once daily | 20-40 mg once daily, depending on symptom control. | Take 30-60 minutes before a meal. |
| Zollinger-Ellison Syndrome | 40 mg twice daily | Individualized; can range from 40 mg twice daily to 240 mg daily. | Doses greater than 80 mg daily should be divided and given twice daily. |
Protonix Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $30 |
| Without Insurance (U.S.) | $320 |
| From CPS | $24 |

