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General Medication Fact Sheet for Qulipta
| Field | Information |
|---|---|
| Medication Name | Qulipta |
| Generic Name | Atogepant |
| Purpose | Used for the preventive treatment of migraine in adults. |
| Mechanism of Action | Calcitonin gene-related peptide (CGRP) receptor antagonist; blocks the binding of CGRP to its receptor. |
| Dosage Forms | Oral tablets |
| Available Strengths | 10 mg, 30 mg, 60 mg |
| Dosage Frequency | Once daily |
| Common Side Effects | Constipation, nausea, fatigue |
| Serious Side Effects | Allergic reactions (rash, itching, swelling), elevated liver enzymes |
| Drug Interactions | Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole, clarithromycin), strong CYP3A4 inducers (e.g., rifampin, phenytoin, carbamazepine) |
| Important Notes | Inform your doctor of any liver problems or medications you are taking. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember unless it is almost time for your next dose. Do not double the dose. |
| Alternatives | Aimovig (erenumab), Emgality (galcanezumab), Ajovy (fremanezumab), Ubrelvy (ubrogepant) |
Qulipta Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Aimovig (erenumab) | CGRP receptor antagonist (monoclonal antibody) | Administered via monthly subcutaneous injection. |
| Emgality (galcanezumab) | CGRP ligand antagonist (monoclonal antibody) | Administered via monthly subcutaneous injection. |
| Ajovy (fremanezumab) | CGRP ligand antagonist (monoclonal antibody) | Administered via monthly or quarterly subcutaneous injection. |
| Ubrelvy (ubrogepant) | CGRP receptor antagonist (gepant) | Used for acute treatment of migraine, not prevention. |
Qulipta Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Constipation | Allergic reactions (rash, itching, swelling) |
| Nausea | Elevated liver enzymes |
| Fatigue | Severe allergic reaction (anaphylaxis) – rare |
Qulipta Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Migraine Prevention | 10 mg, 30 mg, or 60 mg | 10 mg, 30 mg, or 60 mg once daily | Take without regard to food. Follow doctor’s instructions. |
Qulipta Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $25 |
| Without Insurance (U.S.) | $1,100 |
| From CPS | $800 |
