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General Medication Fact Sheet for Rapaflo
| Field | Information |
|---|---|
| Medication Name | Rapaflo |
| Generic Name | Silodosin |
| Purpose | Treats the symptoms of benign prostatic hyperplasia (BPH), also known as enlarged prostate. |
| Mechanism of Action | Selective alpha-1 adrenergic receptor antagonist; relaxes muscles in the prostate and bladder neck to improve urine flow. |
| Dosage Forms | Oral capsules |
| Available Strengths | 4 mg, 8 mg |
| Dosage Frequency | Once daily |
| Common Side Effects | Dizziness, lightheadedness, retrograde ejaculation, nasal congestion. |
| Serious Side Effects | Orthostatic hypotension (drop in blood pressure upon standing), priapism (prolonged erection). |
| Drug Interactions | PDE5 inhibitors (e.g., sildenafil, tadalafil), certain blood pressure medications, strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin). |
| Important Notes | Take after a meal. May cause dizziness, especially when starting treatment or after increasing the dose. Avoid activities requiring alertness until you know how the medication affects you. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember, unless it is almost time for your next dose. Do not double the dose. |
| Alternatives | Tamsulosin (Flomax), Alfuzosin (Uroxatral), Terazosin, Doxazosin, Finasteride (Proscar), Dutasteride (Avodart) |
Rapaflo Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Tamsulosin (Flomax) | Alpha-1 adrenergic receptor antagonist | Similar mechanism of action to silodosin; commonly prescribed for BPH. |
| Alfuzosin (Uroxatral) | Alpha-1 adrenergic receptor antagonist | Another selective alpha-1 blocker for BPH. |
| Terazosin | Alpha-1 adrenergic receptor antagonist | Can also treat high blood pressure. Requires titration to minimize hypotension. |
| Doxazosin | Alpha-1 adrenergic receptor antagonist | Can also treat high blood pressure. Requires titration to minimize hypotension. |
| Finasteride (Proscar) | 5-alpha reductase inhibitor | Reduces prostate size by blocking the conversion of testosterone to dihydrotestosterone (DHT). |
| Dutasteride (Avodart) | 5-alpha reductase inhibitor | Similar to Finasteride, but blocks both type I and type II 5-alpha reductase enzymes. |
Rapaflo Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Dizziness | Orthostatic hypotension (drop in blood pressure upon standing) |
| Lightheadedness | Priapism (prolonged erection) |
| Retrograde ejaculation (semen goes into the bladder instead of out the penis) | Severe allergic reaction (rash, itching, swelling, difficulty breathing) |
| Nasal congestion | Fainting |
| Headache | Intraoperative Floppy Iris Syndrome (IFIS) during cataract surgery |
Rapaflo Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Benign Prostatic Hyperplasia (BPH) | 4 mg | 8 mg once daily | Take after a meal. May need to adjust dose based on tolerability and renal function. |
