Rapamune (Sirolimus)

$78.45 – $1,436.40

Rapamune

Sirolimus

Shipped from Canada Sourced from Canada
Prescription Required
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Rapamune

Sirolimus

Shipped from United Kingdom Sourced from United Kingdom
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Sirolimus (Generic)

Sirolimus

Shipped from Mauritius Sourced from Mauritius
Prescription Required
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Description

General Medication Fact Sheet for Rapamune

Field Information
Medication Name Rapamune
Generic Name Sirolimus
Boxed/Label Warning Increased susceptibility to infection and the possible development of lymphoma and other cancers, as well as potential for serious and/or fatal infections.
Purpose Immunosuppressant used to prevent organ rejection after kidney transplantation and treatment of lymphangioleiomyomatosis (LAM).
Mechanism of Action Inhibits the mammalian target of rapamycin (mTOR), which is a key regulator of cell growth, proliferation, and survival.
Dosage Forms Oral tablets, Oral solution
Available Strengths Tablets: 0.5 mg, 1 mg, 2 mg. Oral solution: 1 mg/mL
Dosage Frequency Once daily, or as directed by a healthcare provider.
Common Side Effects Increased cholesterol and triglycerides, edema, hypertension, acne, rash, abdominal pain, diarrhea, nausea, headache, joint pain.
Serious Side Effects Increased risk of infection, lymphoma and other cancers, kidney problems, lung problems, liver problems, severe allergic reactions, wound healing problems.
Drug Interactions CYP3A4 inhibitors (e.g., ketoconazole, itraconazole), CYP3A4 inducers (e.g., rifampin, phenytoin), grapefruit juice, Cyclosporine, Tacrolimus, vaccines.
Important Notes Monitor blood levels regularly. Avoid live vaccines. Report any signs of infection immediately. Females of reproductive potential should use effective contraception.
Storage Store tablets at room temperature away from moisture and light. Store oral solution in the refrigerator after opening.
Missed Dose Take as soon as you remember unless it is almost time for your next dose. Do not double the dose.
Alternatives Tacrolimus, Cyclosporine, Azathioprine, Mycophenolate mofetil

Rapamune Alternatives

Medication Mechanism of Action Notes
Tacrolimus (Prograf) Calcineurin inhibitor Another immunosuppressant, often used in transplant patients.
Cyclosporine (Neoral, Sandimmune) Calcineurin inhibitor An immunosuppressant used to prevent organ rejection.
Azathioprine (Imuran) Purine synthesis inhibitor An immunosuppressant that works differently than Rapamune.
Mycophenolate mofetil (CellCept) Inhibits purine synthesis An immunosuppressant used to prevent organ rejection.

Rapamune Side Effects

Common Side Effects Serious Side Effects
Increased cholesterol and triglycerides Increased risk of infection
Edema (swelling) Lymphoma and other cancers
Hypertension (high blood pressure) Kidney problems
Acne Lung problems
Rash Liver problems
Abdominal pain Severe allergic reactions
Diarrhea Wound healing problems
Nausea Thrombocytopenia (low platelet count)
Headache Anemia
Joint Pain Proteinuria

Rapamune Dosage Guide

Condition Starting Dose Maintenance Dose Administration Notes
Kidney Transplantation (Adults) Loading dose of 6 mg 2 mg daily Administer with Cyclosporine and corticosteroids during the initial period after transplantation. Adjust dose based on trough levels.
Kidney Transplantation (Children 13 years and older) 3 mg/m²/day Target trough level of 5-15 ng/mL Administer with Cyclosporine and corticosteroids. Adjust dose based on trough levels.
Lymphangioleiomyomatosis (LAM) 2 mg daily Adjust to achieve trough concentration between 5 to 15 ng/mL Adjust dose to maintain target trough concentrations.

Rapamune Price With And Without Insurance

Purchase Context Estimated Price
With Insurance $25
Without Insurance (U.S.) $1,300
From CPS $185
Why Americans Buy Rapamune from Canada Pharmacy Store?

Why Americans Buy Rapamune from Canada Pharmacy Store?

Americans have trouble affording Rapamune due to numerous factors—but at Canada Pharmacy Store, we offer a safe, affordable alternative. That’s why thousands of Americans trust us to fill their prescriptions with real savings and real service.
Money Bag
Big Savings on U.S. Medications
Our customers save up to 80% on their Rapamune prescriptions compared to U.S. pharmacy prices by ordering through licensed Canadian and international pharmacies.
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Free Prescription Transfers
We make it easy! Our pharmacy team can transfer your Rapamune prescriptions directly from your doctor or local pharmacy – completely free of charge.
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Direct Access to Experts

Our licensed pharmacists are available to support you, answer your questions, and help ensure you’re confident in your treatment.

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Referral Discounts

Spread the word—when you refer friends or family, you both save. It’s our way of saying thanks.

Delivery
Discreet U.S. Shipping

All orders are packaged discreetly and shipped securely to your U.S. address, with your privacy and safety as top priorities.

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Trusted by Americans Nationwide

With years of experience and verified medication sources, we’ve become a go-to solution for Americans looking to cut costs without compromising care.

How to Order Rapamune Online

How to Order Rapamune Online

Step 1

Select Your Prescribed Rapamune Dosage

Choose the strength and quantity as directed by your healthcare provider and add it to your cart.

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Step 2

Proceed Through Secure Checkout

Follow the steps to complete your order and provide necessary shipping and payment details.

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Step 3

Upload Your Rapamune Prescription

Submit a prescription from a licensed U.S. healthcare provider that matches your order.

At Canada Pharmacy Store, patient safety comes first. We strictly comply with prescription regulations and do not ship any medication without a valid, verifiable prescription. Orders may be declined if a prescription appears falsified or altered in any way. We take these precautions to protect your health and ensure lawful, responsible practices.

Guarantee
Guarantee Certificate

Our Guarantee When You Buy Rapamune Through Canada Pharmacy Store

At Canada Pharmacy Store, your safety and satisfaction are our top priorities. We supply only authentic, high-quality medications by working exclusively with licensed Canadian pharmacies and trusted international partners. Every order is filled in accordance with strict regulatory standards and includes medication that’s fully approved by Health Canada or other recognized health authorities such as the MHRA (UK), HSA (Singapore), and the Pharmacy Board of Mauritius.

The Rapamune you receive is the same active medication as what’s available in the U.S.—the only difference is the packaging, which reflects its country of origin. Our licensed healthcare professionals review each order carefully to ensure it matches your prescription exactly.
To get Rapamune at a lower price, simply place your order above or give us a call at 1-888-903-2240