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Rasagiline (Generic)
| Azilect Rasagiline | ||||||
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Shipped from Canada | ||||||
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| Select product strength & quantity:
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| Azilect Rasagiline Mesylate | ||||||
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Shipped from Mauritius | ||||||
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General Medication Fact Sheet for Rasagiline
| Field | Information |
|---|---|
| Generic Name | Rasagiline |
| Brand Name Versions | Azilect |
| Purpose | Used to treat symptoms of Parkinson’s disease. |
| Mechanism of Action | Selective irreversible inhibitor of monoamine oxidase type B (MAO-B). |
| Dosage Forms | Oral tablets |
| Available Strengths | 0.5 mg, 1 mg |
| Dosage Frequency | Once daily |
| Common Side Effects | Headache, joint pain, indigestion, depression, flu-like symptoms. |
| Serious Side Effects | High blood pressure, serotonin syndrome, melanoma, hallucinations, unusual uncontrollable movements. |
| Drug Interactions | Other MAO inhibitors, antidepressants (SSRIs, SNRIs, tricyclics), certain pain medications (e.g., tramadol), cough medicines containing dextromethorphan, St. John’s Wort, cyclobenzaprine. |
| Important Notes | May cause dizziness or lightheadedness, especially when rising quickly from a sitting or lying position. Avoid foods high in tyramine (aged cheeses, cured meats, fermented foods) due to risk of hypertensive crisis. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose. |
| Alternatives | Selegiline, Safinamide, Levodopa/Carbidopa, Amantadine, Dopamine Agonists (Pramipexole, Ropinirole) |
Rasagiline Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Selegiline (Eldepryl, Zelapar) | Selective MAO-B inhibitor | Similar to rasagiline; may have a slightly different side effect profile. |
| Safinamide (Xadago) | Selective MAO-B inhibitor and glutamate release modulator | May be used as an add-on treatment to levodopa. |
| Levodopa/Carbidopa (Sinemet) | Dopamine precursor | Converts to dopamine in the brain; a cornerstone of Parkinson’s treatment. |
| Amantadine (Gocovri) | Dopamine promoter and NMDA receptor antagonist | May help with dyskinesias (involuntary movements) in Parkinson’s disease. |
| Dopamine Agonists (Pramipexole, Ropinirole) | Stimulate dopamine receptors | Can be used alone or with levodopa. |
Rasagiline Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Headache | High blood pressure (hypertension) |
| Joint pain | Serotonin syndrome (with certain drug combinations) |
| Indigestion | Melanoma (increased risk reported in studies) |
| Depression | Hallucinations |
| Flu-like symptoms | Unusual uncontrollable movements (dyskinesia) |
| Dizziness | Falling Asleep During Day to Day Activity |
Rasagiline Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Parkinson’s Disease (Monotherapy) | 0.5 mg once daily | 0.5-1 mg once daily | May be taken with or without food. |
| Parkinson’s Disease (Adjunct to Levodopa) | 0.5 mg once daily | 0.5-1 mg once daily | May help reduce “off” time in patients taking levodopa. |
Rasagiline Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $10 |
| Without Insurance (U.S.) | $60 |
| From CPS | $44 |
