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General Medication Fact Sheet for Rectiv Ointment
| Field | Information |
|---|---|
| Medication Name | Rectiv Ointment |
| Generic Name | Nitroglycerin |
| Purpose | Relief of pain associated with chronic anal fissures. |
| Mechanism of Action | Nitroglycerin is a vasodilator that relaxes the smooth muscle of the anal sphincter, increasing blood flow to the anal region and promoting healing of anal fissures. |
| Dosage Forms | Topical Ointment |
| Available Strengths | 0.4% |
| Dosage Frequency | Apply topically to the anal canal every 12 hours for up to 3 weeks. |
| Common Side Effects | Headache, dizziness, lightheadedness, anal burning or itching. |
| Serious Side Effects | Severe headache, significant drop in blood pressure, allergic reactions (rash, itching, swelling, difficulty breathing). |
| Drug Interactions | Phosphodiesterase-5 (PDE5) inhibitors (e.g., sildenafil, tadalafil, vardenafil), other nitrates (e.g., isosorbide dinitrate, isosorbide mononitrate), riociguat. |
| Important Notes | Do not use with PDE5 inhibitors due to risk of severe hypotension. Consult a doctor if you have a history of low blood pressure or migraines. May cause dizziness; avoid activities requiring alertness until effects are known. |
| Storage | Store at room temperature, away from heat and direct light. Keep tightly closed. |
| Missed Dose | Apply as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not apply a double dose. |
| Alternatives | Diltiazem cream, Nifedipine cream, Topical anesthetics (Lidocaine), Botox injections. |
Rectiv Ointment Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Diltiazem cream | Calcium channel blocker, relaxes smooth muscle. | Applied topically to reduce anal sphincter pressure. |
| Nifedipine cream | Calcium channel blocker, relaxes smooth muscle. | Applied topically to reduce anal sphincter pressure. |
| Topical anesthetics (Lidocaine) | Blocks nerve signals in the body. | Provides temporary pain relief. |
| Botox injections | Blocks nerve signals to muscles. | Relaxes anal sphincter to promote healing; administered by a physician. |
Rectiv Ointment Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Headache | Severe headache |
| Dizziness | Significant drop in blood pressure |
| Lightheadedness | Allergic reactions (rash, itching, swelling, difficulty breathing) |
Rectiv Ointment Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Chronic Anal Fissures | Apply 0.25 inch ribbon of ointment. | Apply 0.25 inch ribbon of ointment every 12 hours. | Apply to the anal canal. Use a finger covering, such as plastic wrap. Do not exceed recommended dose. Wash hands after application. |
Rectiv Ointment Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $60 |
| Without Insurance (U.S.) | $700 |
| From Canada | $245 |
