Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
Description
General Medication Fact Sheet for Relafen
| Field | Information |
|---|---|
| Medication Name | Relafen |
| Generic Name | nabumetone |
| Boxed/Label Warning | Nonsteroidal anti-inflammatory drugs (NSAIDs), including nabumetone, cause an increased risk of serious cardiovascular thrombotic events (heart attack and stroke) and serious gastrointestinal (GI) adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. These risks may occur early in treatment and may increase with duration of use. Relafen is contraindicated for the treatment of peri-operative pain in the setting of coronary artery bypass graft (CABG) surgery. |
| Purpose | To relieve the signs and symptoms of osteoarthritis and rheumatoid arthritis. |
| Mechanism of Action | Relafen is a nonsteroidal anti-inflammatory drug (NSAID). It works by inhibiting cyclooxygenase (COX) enzymes, which reduces the production of prostaglandins. Prostaglandins are chemicals that cause pain, fever, and inflammation in the body. |
| Dosage Forms | Tablets |
| Available Strengths | 500 mg, 750 mg |
| Dosage Frequency | Typically started as a single 1000 mg dose once daily. The dose can be adjusted up to 2000 mg per day, given as a single dose or divided into two doses. |
| Common Side Effects | Stomach pain, constipation, diarrhea, gas, heartburn, nausea, dizziness, headache, rash, ringing in the ears (tinnitus). |
| Serious Side Effects | Heart attack, stroke, stomach ulcers or bleeding, new or worsened high blood pressure, kidney problems, liver damage, anemia, and severe skin or allergic reactions. |
| Drug Interactions | Increased risk of bleeding with anticoagulants (e.g., warfarin) and aspirin. Can reduce the effectiveness of blood pressure medications like ACE inhibitors and diuretics. Concurrent use with corticosteroids or other NSAIDs increases the risk of stomach ulcers. |
| Important Notes | Take with food or milk to reduce stomach upset. Use the lowest effective dose for the shortest duration possible to minimize risks. Alcohol can increase the risk of stomach bleeding. |
| Storage | Store at room temperature (68°F to 77°F or 20°C to 25°C) in a tightly closed container, away from moisture and light. |
| Missed Dose | If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not take two doses at once. |
| Alternatives | Celecoxib (Celebrex), Meloxicam (Mobic), Ibuprofen, Naproxen. |
Relafen Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Celecoxib (Celebrex | Selective COX-2 Inhibitor (NSAID) | Designed to have a lower risk of gastrointestinal side effects compared to non-selective NSAIDs, but still carries cardiovascular risks. |
| Meloxicam (Mobic | Preferential COX-2 Inhibitor (NSAID) | Another NSAID that may have a slightly lower risk of GI side effects than some older NSAIDs. Taken once daily. |
| Naproxen (Aleve) | Non-selective NSAID | A widely available over-the-counter and prescription NSAID. May have a lower cardiovascular risk profile compared to some other NSAIDs. |
| Acetaminophen (Tylenol) | Analgesic and Antipyretic | A pain reliever that is not an NSAID. It does not reduce inflammation but is often a first-line choice for osteoarthritis pain due to its safety profile. |
Relafen Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Stomach pain, heartburn, nausea | Cardiovascular Events: Chest pain, shortness of breath, weakness on one side of body, slurred speech |
| Diarrhea or constipation | GI Bleeding: Black, bloody, or tarry stools; coughing up blood or vomit that looks like coffee grounds |
| Dizziness or headache | Severe skin reactions (rash with blistering, peeling) |
| Ringing in the ears (tinnitus) | Signs of kidney or liver problems (jaundice, dark urine, swelling, severe fatigue, little to no urination) |
| Itching or rash | New or worsening high blood pressure |
Relafen Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Osteoarthritis / Rheumatoid Arthritis | 1000 mg once daily. | The dose may be adjusted from 1000 mg to 2000 mg per day. Doses over 1000 mg can be given once daily or divided into two doses (e.g., 750 mg twice daily). | Take with food or milk to reduce the risk of stomach upset. |
Why Americans Buy Relafen from Canada Pharmacy Store?
Why Americans Buy Relafen from Canada Pharmacy Store?
Americans have trouble affording Relafen due to numerous factors—but at Canada Pharmacy Store, we offer a safe, affordable alternative. That’s why thousands of Americans trust us to fill their prescriptions with real savings and real service.
Big Savings on U.S. Medications
Our customers save up to 80% on their Relafen prescriptions compared to U.S. pharmacy prices by ordering through licensed Canadian and international pharmacies.
Free Prescription Transfers
We make it easy! Our pharmacy team can transfer your Relafen prescriptions directly from your doctor or local pharmacy – completely free of charge.
Direct Access to Experts
Our licensed pharmacists are available to support you, answer your questions, and help ensure you’re confident in your treatment.
Referral Discounts
Spread the word—when you refer friends or family, you both save. It’s our way of saying thanks.
Discreet U.S. Shipping
All orders are packaged discreetly and shipped securely to your U.S. address, with your privacy and safety as top priorities.
Trusted by Americans Nationwide
With years of experience and verified medication sources, we’ve become a go-to solution for Americans looking to cut costs without compromising care.
How to Order Relafen Online
How to Order Relafen Online
Step 1
Select Your Prescribed Relafen Dosage
Choose the strength and quantity as directed by your healthcare provider and add it to your cart.
Step 2
Proceed Through Secure Checkout
Follow the steps to complete your order and provide necessary shipping and payment details.
Step 3
Upload Your Relafen Prescription
Submit a prescription from a licensed U.S. healthcare provider that matches your order.
At Canada Pharmacy Store, patient safety comes first. We strictly comply with prescription regulations and do not ship any medication without a valid, verifiable prescription. Orders may be declined if a prescription appears falsified or altered in any way. We take these precautions to protect your health and ensure lawful, responsible practices.
Guarantee
Our Guarantee When You Buy Relafen Through Canada Pharmacy Store
At Canada Pharmacy Store, your safety and satisfaction are our top priorities. We supply only authentic, high-quality medications by working exclusively with licensed Canadian pharmacies and trusted international partners. Every order is filled in accordance with strict regulatory standards and includes medication that’s fully approved by Health Canada or other recognized health authorities such as the MHRA (UK), HSA (Singapore), and the Pharmacy Board of Mauritius.
The Relafen you receive is the same active medication as what’s available in the U.S.—the only difference is the packaging, which reflects its country of origin. Our licensed healthcare professionals review each order carefully to ensure it matches your prescription exactly.
To get Relafen at a lower price, simply place your order above or give us a call at 1-888-903-2240
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