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Renvela (Sevelamer Carbonate)
| Sevelamer Carbonate (Generic) Sevelamer Carbonate | ||||||
Shipped from United Kingdom | ||||||
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| Sevelamer Carbonate (Generic) Sevelamer Carbonate | ||||||
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Shipped from Mauritius | ||||||
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| Select product strength & quantity:
Who is the product for? YouOtherAdd Family Member/PetYou must be logged in to add additional members to the order. Don't have an account? or Add Family Member/PetSign inTo continue, please enter your email address and password that you use for your account. | ||||||
General Medication Fact Sheet for Renvela
| Field | Information |
|---|---|
| Medication Name | Renvela |
| Generic Name | Sevelamer Carbonate |
| Purpose | Phosphate binder used to control serum phosphorus levels in patients with chronic kidney disease (CKD) on dialysis |
| Mechanism of Action | Binds to dietary phosphate in the gastrointestinal tract, preventing its absorption into the bloodstream |
| Dosage Forms | Oral tablets, Oral powder |
| Available Strengths | 800 mg tablets, 0.8 g packets, 2.4 g packets |
| Dosage Frequency | Typically taken three times daily with meals |
| Common Side Effects | Nausea, vomiting, diarrhea, constipation, abdominal pain, flatulence |
| Serious Side Effects | Bowel obstruction, severe constipation, perforation of the bowel |
| Drug Interactions | Ciprofloxacin, Mycophenolate mofetil, Levothyroxine, medications affected by changes in gastrointestinal transit time (e.g., digoxin, warfarin) |
| Important Notes | Take with meals to maximize phosphate binding; separate from other oral medications by at least 1 hour before or 3 hours after Renvela administration |
| Storage | Store at room temperature away from moisture and light |
| Missed Dose | Take the missed dose with your next meal. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose. |
| Alternatives | Fosrenol (lanthanum carbonate), Phoslyra (ferric citrate), calcium acetate, sevelamer hydrochloride |
Renvela Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Fosrenol (lanthanum carbonate) | Binds to dietary phosphate in the GI tract | Chewable tablet; must be taken with meals. |
| Phoslyra (ferric citrate) | Binds to dietary phosphate in the GI tract | Also increases iron levels, which may be beneficial for some patients. |
| Calcium Acetate | Binds to dietary phosphate in the GI tract | Older phosphate binder; may increase calcium levels. |
| Sevelamer Hydrochloride | Binds to dietary phosphate in the GI tract | Similar to sevelamer carbonate, but may have a higher risk of metabolic acidosis. |
Renvela Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Nausea | Bowel obstruction |
| Vomiting | Severe constipation |
| Diarrhea | Perforation of the bowel |
| Constipation | Fecal impaction |
| Abdominal pain | Dysphagia (difficulty swallowing) |
| Flatulence | Esophageal obstruction |
Renvela Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Hyperphosphatemia in CKD (on dialysis) | 800 mg one to two times daily with meals, based on serum phosphorus level | Adjust dose based on serum phosphorus levels; titrate by 0.8 g three times per day at 2-week intervals as needed | Take with meals; monitor serum phosphorus levels regularly. |
