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Resotran (Prucalopride)
| Prucalopride (Generic) Prucalopride Succinate | ||||||
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General Medication Fact Sheet for Resotran
| Field | Information |
|---|---|
| Medication Name | Resotran |
| Generic Name | Prucalopride |
| Purpose | Treatment of chronic idiopathic constipation (CIC) in adults |
| Mechanism of Action | Selective 5-HT4 receptor agonist, stimulating colonic motility |
| Dosage Forms | Oral tablets |
| Available Strengths | 1 mg, 2 mg |
| Dosage Frequency | Once daily |
| Common Side Effects | Headache, nausea, diarrhea, abdominal pain, dizziness |
| Serious Side Effects | Suicidal ideation, depression, gastrointestinal issues (severe diarrhea or abdominal pain), palpitations |
| Drug Interactions | Cisapride, erythromycin, ketoconazole, quinidine |
| Important Notes | Tell your doctor if you have a history of depression or suicidal thoughts. Use caution in patients with severe gastrointestinal conditions. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose. |
| Alternatives | Linaclotide (Linzess), Lubiprostone (Amitiza), Plecanatide (Trulance), Polyethylene Glycol (Miralax) |
Resotran Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Linaclotide (Linzess) | Guanylate cyclase-C agonist | Increases intestinal fluid secretion and accelerates gastrointestinal transit. |
| Lubiprostone (Amitiza) | Chloride channel activator | Increases fluid secretion in the intestine to ease the passage of stool. |
| Plecanatide (Trulance) | Guanylate cyclase-C agonist | Similar mechanism to linaclotide. |
| Polyethylene Glycol (Miralax) | Osmotic laxative | Draws water into the colon to soften the stool and promote bowel movements. |
Resotran Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Headache | Suicidal ideation |
| Nausea | Depression |
| Diarrhea | Severe abdominal pain |
| Abdominal pain | Palpitations |
| Dizziness | Severe diarrhea leading to dehydration |
Resotran Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Chronic Idiopathic Constipation (CIC) | 1 mg or 2 mg | 1 mg or 2 mg once daily | Can be taken with or without food. |
Resotran Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $25 |
| Without Insurance (U.S.) | $750 |
| From CPS | $125 |
