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General Medication Fact Sheet for Restasis Opthalmic Emulsion
| Field | Information |
|---|---|
| Medication Name | Restasis Opthalmic Emulsion |
| Generic Name | Cyclosporine |
| Purpose | To increase tear production in patients whose tear production is presumed to be suppressed due to ocular inflammation associated with keratoconjunctivitis sicca (dry eye). |
| Mechanism of Action | Cyclosporine is an immunomodulator. The exact mechanism of action is not known, but it is thought to act by partially inhibiting T-cell activation and reducing inflammation. |
| Dosage Forms | Ophthalmic emulsion (eye drops) |
| Available Strengths | 0.05% |
| Dosage Frequency | One drop in each eye twice daily, approximately 12 hours apart. |
| Common Side Effects | Ocular burning, stinging, redness, blurred vision, discharge, watery eyes, eye pain, foreign body sensation. |
| Serious Side Effects | Eye infection, severe allergic reactions (rare). |
| Drug Interactions | No known significant drug interactions with Restasis. |
| Important Notes | Remove contact lenses before using Restasis and wait 15 minutes before reinserting them. Use consistently as prescribed for best results. Consult your doctor if symptoms worsen or do not improve. |
| Storage | Store at room temperature between 15°C to 25°C (59°F to 77°F). Protect from light. |
| Missed Dose | If you miss a dose, administer it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose to catch up. |
| Alternatives | Cequa (cyclosporine), Xiidra (lifitegrast), Artificial Tears (various brands), Lacrisert (hydroxypropyl cellulose ophthalmic insert). |
Restasis Opthalmic Emulsion Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Cequa (cyclosporine) | Immunomodulator; reduces inflammation | A higher concentration cyclosporine ophthalmic solution. |
| Xiidra (lifitegrast) | Lymphocyte function-associated antigen-1 (LFA-1) antagonist; reduces inflammation | Another prescription eye drop for dry eye disease. |
| Artificial Tears (various brands) | Lubricates and moisturizes the eye | Available over-the-counter; provides temporary relief of dry eye symptoms. |
| Lacrisert (hydroxypropyl cellulose ophthalmic insert) | Lubricates and retains moisture in the eye | A preservative-free solid insert placed in the lower eye that slowly dissolves to provide continuous lubrication. |
Restasis Opthalmic Emulsion Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Ocular burning | Severe or persistent eye pain or redness |
| Stinging | Signs of a severe allergic reaction (hives, swelling of the face, difficulty breathing) |
| Redness | Significant changes in vision |
| Blurred vision | |
| Discharge | |
| Watery eyes | |
| Eye pain | |
| Foreign body sensation |
Restasis Opthalmic Emulsion Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Keratoconjunctivitis Sicca (Dry Eye) | One drop in each eye | One drop in each eye twice daily | Administer approximately 12 hours apart. Remove contact lenses before use and wait 15 minutes before reinserting. Invert the single-use vial a few times to ensure a uniform, white, opaque emulsion before administering. |
Restasis Opthalmic Emulsion Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $40 |
| Without Insurance (U.S.) | $700 |
| From CPS | $150 |
