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Revia (Naltrexone)
| Naltrexone Hydrochloride (Generic) Naltrexone Hydrochloride | ||||||
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Shipped from Canada | ||||||
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| Naltrexone Hydrochloride (Generic) Naltrexone Hydrochloride | ||||||
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Shipped from Mauritius | ||||||
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| Select product strength & quantity:
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General Medication Fact Sheet for Revia
| Field | Information |
|---|---|
| Medication Name | Revia |
| Generic Name | Naltrexone |
| Boxed/Label Warning | Risk of hepatocellular injury (liver damage), particularly with excessive dosages or pre-existing liver conditions. Warn patients of this risk and monitor liver function tests. |
| Purpose | Treatment of alcohol dependence and opioid dependence. |
| Mechanism of Action | Opioid receptor antagonist; blocks the effects of opioid medications and reduces the craving for alcohol. |
| Dosage Forms | Oral tablets |
| Available Strengths | 50 mg |
| Dosage Frequency | Usually once daily, or as directed by a healthcare provider. |
| Common Side Effects | Nausea, vomiting, headache, anxiety, insomnia. |
| Serious Side Effects | Liver damage, depression, suicidal thoughts, allergic reactions. |
| Drug Interactions | Opioid medications, cough and cold remedies containing opioids. |
| Important Notes | Patients must be opioid-free for at least 7-10 days before starting naltrexone to avoid acute withdrawal symptoms. Monitor liver function. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember unless it is almost time for your next dose. Do not double the dose. |
| Alternatives | Acamprosate, Disulfiram, Vivitrol (naltrexone extended-release injectable suspension), Campral |
Revia Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Acamprosate (Campral) | NMDA receptor antagonist and GABA receptor modulator | Used to maintain abstinence from alcohol; works differently than naltrexone. |
| Disulfiram (Antabuse) | Aldehyde dehydrogenase inhibitor | Causes unpleasant effects (nausea, vomiting, headache) when alcohol is consumed, discouraging drinking. |
| Vivitrol (naltrexone extended-release injectable suspension) | Opioid receptor antagonist | Long-acting injectable form of naltrexone, administered once a month. |
| Campral | Glutamate modulator | Helps to reduce alcohol cravings by normalizing brain activity disrupted by chronic alcohol use. |
Revia Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Nausea | Liver damage |
| Headache | Depression |
| Anxiety | Suicidal thoughts |
| Insomnia | Allergic reactions (rash, itching, swelling, difficulty breathing) |
| Vomiting | Acute opioid withdrawal (if opioids are used while taking naltrexone) |
Revia Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Alcohol Dependence | 25 mg | 50 mg once daily | Ensure patient is opioid-free before starting. |
| Opioid Dependence | 25 mg | 50 mg once daily | Confirm opioid-free status with a naloxone challenge test. |
