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General Medication Fact Sheet for Revolution
| Field | Information |
|---|---|
| Medication Name | Revolution |
| Generic Name | Selamectin |
| Purpose | Topical parasiticide used to prevent heartworm disease, flea infestations, ear mites, and certain types of ticks and worms in dogs and cats. |
| Mechanism of Action | Selamectin interferes with the nerve and muscle function of parasites, leading to their paralysis and death. |
| Dosage Forms | Topical solution |
| Available Strengths | Available in various concentrations based on the animal’s weight (e.g., 6%, 12%). |
| Dosage Frequency | Applied topically once a month. |
| Common Side Effects | Temporary hair loss at the application site, skin irritation, or a transient, localized itching sensation. |
| Serious Side Effects | Excessive salivation, incoordination, vomiting, diarrhea, muscle tremors (rare). |
| Drug Interactions | Generally safe with other medications but consult with a veterinarian before combining with other parasiticides. |
| Important Notes | Use only on the species indicated. Avoid contact with the animal’s eyes and mouth. Wash hands after application. |
| Storage | Store at room temperature, away from heat and direct sunlight. |
| Missed Dose | Apply as soon as you remember, then resume your regular monthly schedule. |
| Alternatives | Advocate (imidacloprid and moxidectin), Frontline (fipronil), Heartgard (ivermectin) for heartworm prevention only. |
Revolution Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Advocate (imidacloprid and moxidectin) | Imidacloprid affects the nerve cells of insects, and moxidectin paralyzes and kills parasites. | Broad-spectrum parasiticide that protects against fleas, heartworms, and intestinal worms. |
| Frontline (fipronil) | Fipronil disrupts the central nervous system of insects. | Primarily used for flea and tick control. |
| Heartgard (ivermectin) | Ivermectin paralyzes and kills heartworm larvae. | Specifically for heartworm prevention; does not protect against fleas or ticks. |
| Bravecto (fluralaner) | Fluralaner disrupts the nervous system of fleas and ticks. | Long-lasting flea and tick protection (up to 12 weeks). |
Revolution Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Temporary hair loss at the application site | Excessive salivation |
| Skin irritation | Incoordination |
| Transient, localized itching | Vomiting |
Revolution Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Heartworm Prevention, Flea Control, Ear Mites, Worms | Based on animal’s weight (refer to product label) | Monthly application based on animal’s weight. | Apply topically to the skin at the base of the neck in front of the shoulder blades. |
