Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
General Medication Fact Sheet for Ritonavir & Lopinavir
| Field | Information |
|---|---|
| Generic Name | Ritonavir & Lopinavir |
| Brand Name Versions | Kaletra |
| Boxed/Label Warning | This medication may cause serious and life-threatening side effects, including liver problems. Tell your doctor if you have or have ever had liver problems. Your doctor may need to monitor your liver function closely. |
| Purpose | Antiretroviral medication used to treat HIV infection |
| Mechanism of Action | Protease inhibitors that block the HIV-1 protease enzyme, preventing viral replication |
| Dosage Forms | Oral tablets, Oral solution |
| Available Strengths | Lopinavir 200mg / Ritonavir 50mg |
| Dosage Frequency | Typically twice daily, or as directed by a healthcare provider |
| Common Side Effects | Diarrhea, nausea, vomiting, abdominal pain, fatigue |
| Serious Side Effects | Liver problems, pancreatitis, high blood sugar, increased cholesterol and triglycerides, heart problems |
| Drug Interactions | Many drugs interact with ritonavir & lopinavir, including other antiretrovirals, statins, antifungals, and some antibiotics. Consult a healthcare provider for a complete list. |
| Important Notes | Take with food to improve absorption. Do not skip doses. This medication does not cure HIV, but it can help control the virus. |
| Storage | Store at room temperature away from moisture and light. Keep the medication in its original container. |
| Missed Dose | Take as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose. |
| Alternatives | Other antiretroviral medications, including other protease inhibitors, nucleoside reverse transcriptase inhibitors (NRTIs), non-nucleoside reverse transcriptase inhibitors (NNRTIs), integrase inhibitors, and entry inhibitors. |
Ritonavir & Lopinavir Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Atazanavir (Reyataz) | Protease Inhibitor | Another protease inhibitor; often boosted with ritonavir. |
| Darunavir (Prezista) | Protease Inhibitor | Another protease inhibitor; often boosted with ritonavir or cobicistat. |
| Dolutegravir (Tivicay) | Integrase Inhibitor | An integrase strand transfer inhibitor (INSTI). |
| Elvitegravir/Cobicistat/Emtricitabine/Tenofovir alafenamide (Genvoya) | Integrase Inhibitor/CYP3A Inhibitor/NRTI | A single-tablet regimen containing an integrase inhibitor and two NRTIs. |
Ritonavir & Lopinavir Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Diarrhea | Liver problems |
| Nausea | Pancreatitis |
| Vomiting | High blood sugar (hyperglycemia) |
| Abdominal pain | Increased cholesterol and triglycerides (hyperlipidemia) |
| Fatigue | Heart problems (e.g., prolonged QT interval) |
| Headache | Severe allergic reactions (rash, itching, swelling, difficulty breathing) |
Ritonavir & Lopinavir Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| HIV Infection (Adults) | Lopinavir 400 mg / Ritonavir 100 mg | Lopinavir 400 mg / Ritonavir 100 mg twice daily | Take with food. Dosage may vary based on other medications. Consult your doctor. |
| HIV Infection (Children) | Dosage is weight-based | Dosage is weight-based, determined by healthcare provider | Take with food. Consult a pediatrician or HIV specialist. |
Ritonavir & Lopinavir Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $70 |
| Without Insurance (U.S.) | $845 |
| From CPS | $40 |
