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General Medication Fact Sheet for Rulid
| Field | Information |
|---|---|
| Medication Name | Rulid |
| Generic Name | Roxithromycin |
| Purpose | Macrolide antibiotic used to treat bacterial infections |
| Mechanism of Action | Inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit |
| Dosage Forms | Oral tablets |
| Available Strengths | 150 mg, 300 mg |
| Dosage Frequency | Typically once or twice daily, as directed by a healthcare provider |
| Common Side Effects | Nausea, vomiting, abdominal pain, diarrhea, headache, dizziness |
| Serious Side Effects | Severe allergic reactions (rash, itching, swelling, difficulty breathing), liver problems (jaundice, dark urine), heart rhythm problems (QT prolongation) |
| Drug Interactions | Ergotamine, cisapride, pimozide, warfarin, digoxin, theophylline |
| Important Notes | Take as prescribed for the full course of treatment, even if symptoms improve; consult a doctor if you have liver or heart problems |
| Storage | Store at room temperature away from moisture and light |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Azithromycin, Clarithromycin, Erythromycin, Amoxicillin |
Rulid Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Azithromycin (Zithromax) | Macrolide antibiotic; inhibits bacterial protein synthesis | Often given as a shorter course of treatment. |
| Clarithromycin (Biaxin) | Macrolide antibiotic; inhibits bacterial protein synthesis | Similar to roxithromycin, but may have different interactions. |
| Erythromycin | Macrolide antibiotic; inhibits bacterial protein synthesis | Older macrolide antibiotic with a broader spectrum. |
| Amoxicillin | Penicillin antibiotic; inhibits bacterial cell wall synthesis | Effective against many bacterial infections; not a macrolide. |
Rulid Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Nausea | Severe allergic reactions (rash, itching, swelling, difficulty breathing) |
| Vomiting | Liver problems (jaundice, dark urine) |
| Abdominal pain | Heart rhythm problems (QT prolongation) |
| Diarrhea | Severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis) |
| Headache | C. difficile-associated diarrhea |
Rulid Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Respiratory Tract Infections | 150 mg | 150 mg twice daily or 300 mg once daily | Take before meals. |
| Skin Infections | 150 mg | 150 mg twice daily or 300 mg once daily | Take before meals. |
| Genitourinary Infections | 150 mg | 150 mg twice daily or 300 mg once daily | Take before meals. |
