Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
Description
General Medication Fact Sheet for Saphris
| Field | Information |
|---|---|
| Medication Name | Saphris |
| Generic Name | Asenapine |
| Boxed/Label Warning | Increased risk of death in elderly people with dementia-related psychosis. |
| Purpose | Treatment of schizophrenia and bipolar I disorder (manic or mixed episodes). |
| Mechanism of Action | Antagonizes dopamine D2 and serotonin 5-HT2A receptors in the brain. |
| Dosage Forms | Sublingual tablets |
| Available Strengths | 2.5 mg, 5 mg, 10 mg |
| Dosage Frequency | Typically twice daily, or as directed by a healthcare provider. |
| Common Side Effects | Drowsiness, dizziness, anxiety, increased appetite, weight gain, extrapyramidal symptoms (EPS). |
| Serious Side Effects | Neuroleptic Malignant Syndrome (NMS), tardive dyskinesia, hyperglycemia, diabetes, hyperlipidemia, orthostatic hypotension, seizures, suicidal thoughts/behaviors. |
| Drug Interactions | Other CNS depressants (e.g., alcohol, benzodiazepines), antihypertensives, dopamine agonists, CYP1A2 inhibitors/inducers. |
| Important Notes | Do not eat or drink for 10 minutes after taking the sublingual tablet. Monitor for metabolic changes (weight, glucose, lipids). Use caution when driving or operating machinery. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember unless it is almost time for your next dose. Do not double the dose. |
| Alternatives | Risperidone (Risperdal), Quetiapine (Seroquel), Olanzapine (Zyprexa), Aripiprazole (Abilify) |
Saphris Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Risperidone (Risperdal) | Dopamine D2 and serotonin 5-HT2A receptor antagonist | Available in oral and injectable forms. |
| Quetiapine (Seroquel) | Dopamine D1, D2, and serotonin 5-HT1A, 5-HT2A receptor antagonist | Also used for bipolar disorder and major depressive disorder. |
| Olanzapine (Zyprexa) | Dopamine and serotonin antagonist | Known for weight gain and metabolic side effects. |
| Aripiprazole (Abilify) | Dopamine D2 partial agonist and serotonin 5-HT1A agonist | May have a lower risk of some side effects compared to other antipsychotics. |
Saphris Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Drowsiness | Neuroleptic Malignant Syndrome (NMS) |
| Dizziness | Tardive dyskinesia |
| Anxiety | Hyperglycemia/Diabetes |
| Increased appetite | Hyperlipidemia |
| Weight gain | Orthostatic hypotension |
| Extrapyramidal symptoms (EPS) | Seizures |
| Numbness in mouth | Suicidal thoughts/behaviors |
Saphris Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Schizophrenia | 5 mg twice daily | 5-10 mg twice daily | Administer sublingually; do not eat or drink for 10 minutes after administration. |
| Bipolar I Disorder (Manic or Mixed) | 5 mg twice daily | 5-10 mg twice daily | Administer sublingually; do not eat or drink for 10 minutes after administration. |
Saphris Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $100 |
| Without Insurance (U.S.) | $1,250 |
| From CPS | $276 |
Why Americans Buy Saphris from Canada Pharmacy Store?
Why Americans Buy Saphris from Canada Pharmacy Store?
Americans have trouble affording Saphris due to numerous factors—but at Canada Pharmacy Store, we offer a safe, affordable alternative. That’s why thousands of Americans trust us to fill their prescriptions with real savings and real service.
Big Savings on U.S. Medications
Our customers save up to 80% on their Saphris prescriptions compared to U.S. pharmacy prices by ordering through licensed Canadian and international pharmacies.
Free Prescription Transfers
We make it easy! Our pharmacy team can transfer your Saphris prescriptions directly from your doctor or local pharmacy – completely free of charge.
Direct Access to Experts
Our licensed pharmacists are available to support you, answer your questions, and help ensure you’re confident in your treatment.
Referral Discounts
Spread the word—when you refer friends or family, you both save. It’s our way of saying thanks.
Discreet U.S. Shipping
All orders are packaged discreetly and shipped securely to your U.S. address, with your privacy and safety as top priorities.
Trusted by Americans Nationwide
With years of experience and verified medication sources, we’ve become a go-to solution for Americans looking to cut costs without compromising care.
How to Order Saphris Online
How to Order Saphris Online
Step 1
Select Your Prescribed Saphris Dosage
Choose the strength and quantity as directed by your healthcare provider and add it to your cart.
Step 2
Proceed Through Secure Checkout
Follow the steps to complete your order and provide necessary shipping and payment details.
Step 3
Upload Your Saphris Prescription
Submit a prescription from a licensed U.S. healthcare provider that matches your order.
At Canada Pharmacy Store, patient safety comes first. We strictly comply with prescription regulations and do not ship any medication without a valid, verifiable prescription. Orders may be declined if a prescription appears falsified or altered in any way. We take these precautions to protect your health and ensure lawful, responsible practices.
Guarantee
Our Guarantee When You Buy Saphris Through Canada Pharmacy Store
At Canada Pharmacy Store, your safety and satisfaction are our top priorities. We supply only authentic, high-quality medications by working exclusively with licensed Canadian pharmacies and trusted international partners. Every order is filled in accordance with strict regulatory standards and includes medication that’s fully approved by Health Canada or other recognized health authorities such as the MHRA (UK), HSA (Singapore), and the Pharmacy Board of Mauritius.
The Saphris you receive is the same active medication as what’s available in the U.S.—the only difference is the packaging, which reflects its country of origin. Our licensed healthcare professionals review each order carefully to ensure it matches your prescription exactly.
To get Saphris at a lower price, simply place your order above or give us a call at 1-888-903-2240
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