Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
Saxagliptin (Generic)
| Kombiglyze XR Saxagliptin Hydrochloride, Metformin Hydrochloride | ||||||
|
Shipped from Mauritius | ||||||
| | ||||||
| Select product strength & quantity:
Who is the product for? YouOtherAdd Family Member/PetYou must be logged in to add additional members to the order. Don't have an account? or Add Family Member/PetSign inTo continue, please enter your email address and password that you use for your account. | ||||||
| Select product strength & quantity:
Who is the product for? YouOtherAdd Family Member/PetYou must be logged in to add additional members to the order. Don't have an account? or Add Family Member/PetSign inTo continue, please enter your email address and password that you use for your account. | ||||||
| Komboglyze Metformin Hydrochloride, Saxagliptin Hydrochloride | ||||||
|
Shipped from Canada | ||||||
| | ||||||
| Select product strength & quantity:
Who is the product for? YouOtherAdd Family Member/PetYou must be logged in to add additional members to the order. Don't have an account? or Add Family Member/PetSign inTo continue, please enter your email address and password that you use for your account. | ||||||
| Select product strength & quantity:
Who is the product for? YouOtherAdd Family Member/PetYou must be logged in to add additional members to the order. Don't have an account? or Add Family Member/PetSign inTo continue, please enter your email address and password that you use for your account. | ||||||
| Select product strength & quantity:
Who is the product for? YouOtherAdd Family Member/PetYou must be logged in to add additional members to the order. Don't have an account? or Add Family Member/PetSign inTo continue, please enter your email address and password that you use for your account. | ||||||
| Onglyza Saxagliptin Hydrochloride | ||||||
|
Shipped from Canada | ||||||
| | ||||||
| Select product strength & quantity:
Who is the product for? YouOtherAdd Family Member/PetYou must be logged in to add additional members to the order. Don't have an account? or Add Family Member/PetSign inTo continue, please enter your email address and password that you use for your account. | ||||||
| Select product strength & quantity:
Who is the product for? YouOtherAdd Family Member/PetYou must be logged in to add additional members to the order. Don't have an account? or Add Family Member/PetSign inTo continue, please enter your email address and password that you use for your account. | ||||||
| Onglyza Saxagliptin Hydrochloride | ||||||
|
Shipped from Mauritius | ||||||
| | ||||||
| Select product strength & quantity:
Who is the product for? YouOtherAdd Family Member/PetYou must be logged in to add additional members to the order. Don't have an account? or Add Family Member/PetSign inTo continue, please enter your email address and password that you use for your account. | ||||||
| Select product strength & quantity:
Who is the product for? YouOtherAdd Family Member/PetYou must be logged in to add additional members to the order. Don't have an account? or Add Family Member/PetSign inTo continue, please enter your email address and password that you use for your account. | ||||||
General Medication Fact Sheet for Saxagliptin
| Field | Information |
|---|---|
| Generic Name | Saxagliptin |
| Brand Name Versions | Onglyza |
| Purpose | Used to treat type 2 diabetes mellitus by lowering blood sugar levels |
| Mechanism of Action | Inhibits dipeptidyl peptidase-4 (DPP-4), increasing incretin hormone levels and stimulating insulin release |
| Dosage Forms | Oral tablets |
| Available Strengths | 2.5 mg, 5 mg |
| Dosage Frequency | Once daily |
| Common Side Effects | Upper respiratory tract infection, urinary tract infection, headache |
| Serious Side Effects | Pancreatitis, severe joint pain, heart failure |
| Drug Interactions | Insulin, sulfonylureas (e.g., Glipizide), CYP3A4/5 inhibitors (e.g., ketoconazole) |
| Important Notes | Monitor for signs of heart failure. Not for use in type 1 diabetes or diabetic ketoacidosis. |
| Storage | Store at room temperature away from moisture and light |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Sitagliptin, Metformin, Glipizide, Empagliflozin |
Saxagliptin Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Sitagliptin (Januvia) | DPP-4 inhibitor | Similar mechanism to saxagliptin. |
| Metformin (Glucophage) | Decreases glucose production in the liver and improves insulin sensitivity. | First-line treatment for type 2 diabetes. |
| Glipizide (Glucotrol) | Sulfonylurea; stimulates insulin release from the pancreas. | May cause hypoglycemia. |
| Empagliflozin (Jardiance) | SGLT2 inhibitor; increases glucose excretion in the urine. | May have cardiovascular benefits. |
Saxagliptin Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Upper respiratory tract infection | Pancreatitis |
| Urinary tract infection | Severe joint pain |
| Headache | Heart failure |
| Nausea | Allergic reactions (rash, itching, swelling) |
| Swelling in the legs or ankles | Kidney problems |
Saxagliptin Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Type 2 Diabetes | 2.5 mg or 5 mg | 2.5 mg or 5 mg once daily | Can be taken with or without food. Adjust dose based on kidney function. |
