Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
Description
General Medication Fact Sheet for Scemblix
| Field | Information |
|---|---|
| Medication Name | Scemblix |
| Generic Name | Asciminib |
| Boxed/Label Warning | QTc Prolongation, Ischemic Cardiovascular Events, Occlusive Arterial Events, Pancreatitis, Embryo-Fetal Toxicity |
| Purpose | Treatment of Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) in chronic phase |
| Mechanism of Action | Specifically targets the ABL myristoyl pocket (STAMP) of the BCR-ABL1 protein, inhibiting its activity |
| Dosage Forms | Oral tablets |
| Available Strengths | 20 mg, 40 mg |
| Dosage Frequency | Twice daily |
| Common Side Effects | Upper respiratory tract infections, musculoskeletal pain, fatigue, nausea, diarrhea, abdominal pain, rash, increased pancreatic enzymes |
| Serious Side Effects | QTc prolongation, ischemic cardiovascular events, occlusive arterial events, pancreatitis, embryo-fetal toxicity, myelosuppression, hypertension, hyperlipidemia |
| Drug Interactions | Strong CYP3A4 inhibitors (e.g., ketoconazole), strong CYP3A4 inducers (e.g., rifampin), sensitive CYP3A4 substrates, drugs that prolong the QTc interval |
| Important Notes | Monitor ECG for QTc prolongation. Monitor for cardiovascular events and pancreatitis. Women of reproductive potential should use effective contraception. |
| Storage | Store at room temperature, between 68°F to 77°F (20°C to 25°C). |
| Missed Dose | Take the missed dose as soon as you remember unless it is less than 6 hours until your next scheduled dose. Do not take two doses at the same time to make up for the missed dose. |
| Alternatives | Imatinib (Gleevec), Dasatinib (Sprycel), Nilotinib (Tasigna), Bosutinib (Bosulif) |
Scemblix Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Imatinib (Gleevec) | Tyrosine kinase inhibitor, inhibits BCR-ABL | First-generation TKI; effective but resistance can develop. |
| Dasatinib (Sprycel) | Tyrosine kinase inhibitor, inhibits BCR-ABL and other kinases | Second-generation TKI; more potent than Imatinib. |
| Nilotinib (Tasigna) | Tyrosine kinase inhibitor, inhibits BCR-ABL | Second-generation TKI; more potent than Imatinib. |
| Bosutinib (Bosulif) | Tyrosine kinase inhibitor, inhibits BCR-ABL and other kinases | Second-generation TKI; may have different side effect profile. |
Scemblix Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Upper respiratory tract infections | QTc prolongation |
| Musculoskeletal pain | Ischemic cardiovascular events |
| Fatigue | Occlusive arterial events |
| Nausea | Pancreatitis |
| Diarrhea | Myelosuppression (decreased blood cell counts) |
| Abdominal pain | Hypertension |
| Rash | Hyperlipidemia |
| Increased pancreatic enzymes | Embryo-Fetal Toxicity |
Scemblix Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Ph+ CML in Chronic Phase (Previously Treated) | 40 mg | 40 mg twice daily | Take orally with or without food. Swallow tablets whole; do not crush, cut, or chew. |
| Ph+ CML in Chronic Phase (Newly Diagnosed) | 80 mg | 80 mg twice daily | Take orally with or without food. Swallow tablets whole; do not crush, cut, or chew. |
Scemblix Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $50 |
| Without Insurance (U.S.) | $22,900 |
| From CPS | $5,954 |
Why Americans Buy Scemblix from Canada Pharmacy Store?
Why Americans Buy Scemblix from Canada Pharmacy Store?
Americans have trouble affording Scemblix due to numerous factors—but at Canada Pharmacy Store, we offer a safe, affordable alternative. That’s why thousands of Americans trust us to fill their prescriptions with real savings and real service.
Big Savings on U.S. Medications
Our customers save up to 80% on their Scemblix prescriptions compared to U.S. pharmacy prices by ordering through licensed Canadian and international pharmacies.
Free Prescription Transfers
We make it easy! Our pharmacy team can transfer your Scemblix prescriptions directly from your doctor or local pharmacy – completely free of charge.
Direct Access to Experts
Our licensed pharmacists are available to support you, answer your questions, and help ensure you’re confident in your treatment.
Referral Discounts
Spread the word—when you refer friends or family, you both save. It’s our way of saying thanks.
Discreet U.S. Shipping
All orders are packaged discreetly and shipped securely to your U.S. address, with your privacy and safety as top priorities.
Trusted by Americans Nationwide
With years of experience and verified medication sources, we’ve become a go-to solution for Americans looking to cut costs without compromising care.
How to Order Scemblix Online
How to Order Scemblix Online
Step 1
Select Your Prescribed Scemblix Dosage
Choose the strength and quantity as directed by your healthcare provider and add it to your cart.
Step 2
Proceed Through Secure Checkout
Follow the steps to complete your order and provide necessary shipping and payment details.
Step 3
Upload Your Scemblix Prescription
Submit a prescription from a licensed U.S. healthcare provider that matches your order.
At Canada Pharmacy Store, patient safety comes first. We strictly comply with prescription regulations and do not ship any medication without a valid, verifiable prescription. Orders may be declined if a prescription appears falsified or altered in any way. We take these precautions to protect your health and ensure lawful, responsible practices.
Guarantee
Our Guarantee When You Buy Scemblix Through Canada Pharmacy Store
At Canada Pharmacy Store, your safety and satisfaction are our top priorities. We supply only authentic, high-quality medications by working exclusively with licensed Canadian pharmacies and trusted international partners. Every order is filled in accordance with strict regulatory standards and includes medication that’s fully approved by Health Canada or other recognized health authorities such as the MHRA (UK), HSA (Singapore), and the Pharmacy Board of Mauritius.
The Scemblix you receive is the same active medication as what’s available in the U.S.—the only difference is the packaging, which reflects its country of origin. Our licensed healthcare professionals review each order carefully to ensure it matches your prescription exactly.
To get Scemblix at a lower price, simply place your order above or give us a call at 1-888-903-2240
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