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General Medication Fact Sheet for Seebri
| Field | Information |
|---|---|
| Medication Name | Seebri |
| Generic Name | Glycopyrronium |
| Purpose | Long-acting muscarinic antagonist (LAMA) used for the maintenance treatment of chronic obstructive pulmonary disease (COPD) to reduce airflow obstruction and exacerbations. |
| Mechanism of Action | Glycopyrronium blocks the action of acetylcholine at muscarinic receptors in the airways, leading to bronchodilation and reduced mucus production. |
| Dosage Forms | Inhalation capsule with a Neohaler device |
| Available Strengths | 50 mcg per capsule |
| Dosage Frequency | Once daily |
| Common Side Effects | Dry mouth, cough, upper respiratory tract infection, urinary retention. |
| Serious Side Effects | Paradoxical bronchospasm, glaucoma, urinary retention. |
| Drug Interactions | Other anticholinergic drugs. Use with caution with drugs that can cause urinary retention or narrow-angle glaucoma. |
| Important Notes | Not for acute bronchospasm relief. Use with a Neohaler device. Do not swallow the capsules. Rinse mouth after each use. |
| Storage | Store at room temperature away from moisture and light. Keep capsules in blister pack until ready to use. |
| Missed Dose | Take as soon as you remember, but do not take two doses at once. Resume your regular schedule the next day. |
| Alternatives | Spiriva (tiotropium), Incruse Ellipta (umeclidinium), Tudorza Pressair (aclidinium) |
Seebri Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Spiriva (tiotropium) | Long-acting muscarinic antagonist (LAMA) | Another LAMA used for COPD maintenance treatment. Available as a HandiHaler or Respimat inhaler. |
| Incruse Ellipta (umeclidinium) | Long-acting muscarinic antagonist (LAMA) | Once-daily LAMA delivered via the Ellipta inhaler. |
| Tudorza Pressair (aclidinium) | Long-acting muscarinic antagonist (LAMA) | Twice-daily LAMA delivered via the Pressair inhaler. |
Seebri Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Dry mouth | Paradoxical bronchospasm |
| Cough | Glaucoma (narrow-angle) |
| Upper respiratory tract infection | Urinary retention |
| Urinary retention | Severe allergic reactions (rash, itching, swelling, difficulty breathing) |
Seebri Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| COPD | 50 mcg | 50 mcg once daily | Use with a Neohaler device. Inhale the contents of one capsule once daily. Do not swallow capsule. |
Seebri Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $50 |
| Without Insurance (U.S.) | $350 |
| From CPS | $86.40 |
