Septra (Sulfamethoxazole & Trimethoprim)

$20.00 – $122.15

Septra

Sulfamethoxazole, Trimethoprim

Shipped from Canada Sourced from Canada
Prescription Required
Select product strength & quantity:

Septra DS

Sulfamethoxazole, Trimethoprim

Shipped from Canada Sourced from Canada
Prescription Required
Select product strength & quantity:

Septra Injection

Sulfamethoxazole, Trimethoprim

Shipped from Canada Sourced from Canada
Prescription Required
Select product strength & quantity:
Select product strength & quantity:

Septrin

Sulfamethoxazole, Trimethoprim

Shipped from United Kingdom Sourced from United Kingdom
Prescription Required
Select product strength & quantity:

Septrin Forte

Sulfamethoxazole, Trimethoprim

Shipped from United Kingdom Sourced from United Kingdom
Prescription Required
Select product strength & quantity:

Sulfamethoxazole (Generic)

Sulfamethoxazole, Trimethoprim

Shipped from Canada Sourced from Canada
Prescription Required
Select product strength & quantity:

Sulfamethoxazole / Trimethoprim (Generic)

Sulfamethoxazole, Trimethoprim

Shipped from Canada Sourced from Canada
Prescription Required
Select product strength & quantity:
Select product strength & quantity:
Description

General Medication Fact Sheet for Septra

Field Information
Medication Name Septra
Generic Name Sulfamethoxazole and Trimethoprim
Boxed/Label Warning May cause serious skin reactions, blood disorders, liver damage, or kidney damage. Use with caution in patients with pre-existing blood disorders or impaired kidney or liver function.
Purpose Antibiotic used to treat various bacterial infections
Mechanism of Action Sulfamethoxazole inhibits bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA). Trimethoprim inhibits dihydrofolate reductase, another step in the folic acid synthesis pathway. This synergistic action blocks two consecutive steps in the bacterial folic acid pathway, leading to effective bacterial growth inhibition.
Dosage Forms Oral tablets, Oral suspension
Available Strengths Tablets: 400 mg sulfamethoxazole/80 mg trimethoprim, 800 mg sulfamethoxazole/160 mg trimethoprim; Suspension: 200 mg sulfamethoxazole/40 mg trimethoprim per 5 mL
Dosage Frequency Typically twice daily, every 12 hours, or as directed by a healthcare provider
Common Side Effects Nausea, vomiting, diarrhea, loss of appetite
Serious Side Effects Severe skin rash (Stevens-Johnson syndrome, toxic epidermal necrolysis), blood disorders (thrombocytopenia, leukopenia, anemia), liver problems, kidney problems, allergic reactions, *C. difficile*-associated diarrhea
Drug Interactions Warfarin, phenytoin, methotrexate, sulfonylureas, diuretics (especially thiazides), ACE inhibitors/ARBs
Important Notes Drink plenty of water while taking this medication. May increase sensitivity to sunlight. Complete the full course of treatment, even if you feel better.
Storage Store at room temperature away from moisture and light
Missed Dose Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose.
Alternatives Amoxicillin, Ciprofloxacin, Doxycycline, Cephalexin

Septra Alternatives

Medication Mechanism of Action Notes
Amoxicillin Inhibits bacterial cell wall synthesis A penicillin antibiotic, effective against many gram-positive bacteria.
Ciprofloxacin (Cipro) Inhibits bacterial DNA gyrase and topoisomerase IV A fluoroquinolone antibiotic, effective against many gram-negative bacteria.
Doxycycline Inhibits bacterial protein synthesis A tetracycline antibiotic, effective against a broad range of bacteria.
Cephalexin (Keflex) Inhibits bacterial cell wall synthesis A cephalosporin antibiotic, effective against many gram-positive bacteria.

Septra Side Effects

Common Side Effects Serious Side Effects
Nausea Severe skin rash (Stevens-Johnson syndrome, toxic epidermal necrolysis)
Vomiting Blood disorders (thrombocytopenia, leukopenia, anemia)
Diarrhea Liver problems (jaundice, elevated liver enzymes)
Loss of appetite Kidney problems (increased creatinine, kidney failure)
Headache Allergic reactions (rash, itching, swelling, difficulty breathing)
Increased sensitivity to sunlight *C. difficile*-associated diarrhea

Septra Dosage Guide

Condition Starting Dose Maintenance Dose Administration Notes
Urinary Tract Infection (UTI) 1 DS (800/160 mg) tablet 1 DS (800/160 mg) tablet every 12 hours Take with a full glass of water. Complete the full course of treatment.
Pneumocystis Pneumonia (PCP) Treatment 15-20 mg (TMP) / kg / day Divided every 6-8 hours For severe infections. Dosing is based on trimethoprim (TMP) component.
Pneumocystis Pneumonia (PCP) Prophylaxis 1 DS (800/160 mg) tablet 1 DS (800/160 mg) tablet once daily For prevention in immunocompromised individuals.
Why Americans Buy Septra from Canada Pharmacy Store?

Why Americans Buy Septra from Canada Pharmacy Store?

Americans have trouble affording Septra due to numerous factors—but at Canada Pharmacy Store, we offer a safe, affordable alternative. That’s why thousands of Americans trust us to fill their prescriptions with real savings and real service.
Money Bag
Big Savings on U.S. Medications
Our customers save up to 80% on their Septra prescriptions compared to U.S. pharmacy prices by ordering through licensed Canadian and international pharmacies.
No
Free Prescription Transfers
We make it easy! Our pharmacy team can transfer your Septra prescriptions directly from your doctor or local pharmacy – completely free of charge.
Strategy
Direct Access to Experts

Our licensed pharmacists are available to support you, answer your questions, and help ensure you’re confident in your treatment.

Referral
Referral Discounts

Spread the word—when you refer friends or family, you both save. It’s our way of saying thanks.

Delivery
Discreet U.S. Shipping

All orders are packaged discreetly and shipped securely to your U.S. address, with your privacy and safety as top priorities.

Trust 1
Trusted by Americans Nationwide

With years of experience and verified medication sources, we’ve become a go-to solution for Americans looking to cut costs without compromising care.

How to Order Septra Online

How to Order Septra Online

Step 1

Select Your Prescribed Septra Dosage

Choose the strength and quantity as directed by your healthcare provider and add it to your cart.

Arrows 13937717

Step 2

Proceed Through Secure Checkout

Follow the steps to complete your order and provide necessary shipping and payment details.

Arrows 13937717

Step 3

Upload Your Septra Prescription

Submit a prescription from a licensed U.S. healthcare provider that matches your order.

At Canada Pharmacy Store, patient safety comes first. We strictly comply with prescription regulations and do not ship any medication without a valid, verifiable prescription. Orders may be declined if a prescription appears falsified or altered in any way. We take these precautions to protect your health and ensure lawful, responsible practices.

Guarantee
Guarantee Certificate

Our Guarantee When You Buy Septra Through Canada Pharmacy Store

At Canada Pharmacy Store, your safety and satisfaction are our top priorities. We supply only authentic, high-quality medications by working exclusively with licensed Canadian pharmacies and trusted international partners. Every order is filled in accordance with strict regulatory standards and includes medication that’s fully approved by Health Canada or other recognized health authorities such as the MHRA (UK), HSA (Singapore), and the Pharmacy Board of Mauritius.

The Septra you receive is the same active medication as what’s available in the U.S.—the only difference is the packaging, which reflects its country of origin. Our licensed healthcare professionals review each order carefully to ensure it matches your prescription exactly.
To get Septra at a lower price, simply place your order above or give us a call at 1-888-903-2240