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General Medication Fact Sheet for Solian
| Field | Information |
|---|---|
| Medication Name | Solian |
| Generic Name | Amisulpride |
| Boxed/Label Warning | Increased mortality in elderly patients with dementia-related psychosis. |
| Purpose | Antipsychotic medication used to treat schizophrenia and other psychotic disorders. |
| Mechanism of Action | Selectively blocks dopamine D2/D3 receptors in the brain. |
| Dosage Forms | Oral tablets |
| Available Strengths | 50 mg, 100 mg, 200 mg, 400 mg |
| Dosage Frequency | Typically once or twice daily, as directed by a healthcare provider. |
| Common Side Effects | Insomnia, anxiety, weight gain, nausea, constipation, increased prolactin levels. |
| Serious Side Effects | Neuroleptic Malignant Syndrome (NMS), tardive dyskinesia, QT prolongation, seizures, blood clots. |
| Drug Interactions | Alcohol, other antipsychotics, antiarrhythmics (e.g., amiodarone), certain antibiotics (e.g., moxifloxacin), levodopa. |
| Important Notes | May cause drowsiness; use caution when driving or operating machinery. Monitor for signs of NMS or tardive dyskinesia. Consult a doctor if you have heart problems or a history of seizures. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember, unless it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Risperidone (Risperdal), Quetiapine (Seroquel), Aripiprazole (Abilify), Olanzapine (Zyprexa) |
Solian Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Risperidone (Risperdal) | Dopamine and serotonin antagonist | Atypical antipsychotic; may have fewer extrapyramidal side effects than older antipsychotics. |
| Quetiapine (Seroquel) | Dopamine and serotonin antagonist | Atypical antipsychotic; often used for both schizophrenia and bipolar disorder. |
| Aripiprazole (Abilify) | Dopamine partial agonist and serotonin antagonist | Atypical antipsychotic; has a unique mechanism of action compared to other antipsychotics. |
| Olanzapine (Zyprexa) | Dopamine and serotonin antagonist | Atypical antipsychotic; known for its potential for weight gain. |
Solian Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Insomnia | Neuroleptic Malignant Syndrome (NMS) |
| Anxiety | Tardive dyskinesia |
| Weight gain | QT prolongation |
| Nausea | Seizures |
| Constipation | Blood clots |
| Increased prolactin levels | Increased mortality in elderly patients with dementia-related psychosis |
Solian Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Schizophrenia (Acute Episode) | 50-300 mg daily | 400-800 mg daily, adjusted based on response | May be administered once or twice daily. |
| Schizophrenia (Maintenance) | 50-300 mg daily | Adjusted based on individual response | Lower doses may be sufficient for maintenance. |
Solian Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $30 |
| Without Insurance (U.S.) | $150 |
| From CPS | $55 |
