Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
General Medication Fact Sheet for Solifenacin
| Field | Information |
|---|---|
| Generic Name | Solifenacin |
| Brand Name Versions | Vesicare |
| Purpose | Treatment of overactive bladder (OAB) with symptoms of urinary frequency, urgency, and urge incontinence. |
| Mechanism of Action | Anticholinergic agent that reduces bladder muscle contractions by blocking muscarinic receptors. |
| Dosage Forms | Oral tablets |
| Available Strengths | 5 mg, 10 mg |
| Dosage Frequency | Once daily |
| Common Side Effects | Dry mouth, constipation, blurred vision, urinary retention |
| Serious Side Effects | Severe allergic reactions (rash, itching, swelling), heatstroke (decreased sweating), hallucinations |
| Drug Interactions | Other anticholinergic drugs, CYP3A4 inhibitors (e.g., ketoconazole), digoxin |
| Important Notes | Use caution when driving or operating machinery; may impair cognitive function. Avoid use in patients with narrow-angle glaucoma or urinary retention. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Oxybutynin, Tolterodine, Mirabegron, Fesoterodine |
Solifenacin Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Oxybutynin (Ditropan) | Anticholinergic; relaxes bladder muscles. | Available as a tablet, syrup, or transdermal patch. |
| Tolterodine (Detrol) | Anticholinergic; reduces bladder contractions. | Generally has fewer side effects than Oxybutynin. |
| Mirabegron (Myrbetriq) | Beta-3 adrenergic agonist; relaxes bladder muscles. | May be an option for patients who cannot tolerate anticholinergics. |
| Fesoterodine (Toviaz) | Anticholinergic; similar to Tolterodine. | Extended-release formulation for once-daily dosing. |
Solifenacin Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Dry mouth | Severe allergic reactions (rash, itching, swelling) |
| Constipation | Heatstroke (decreased sweating) |
| Blurred vision | Hallucinations |
| Urinary retention | Increased risk of falls in elderly patients |
| Headache | Cognitive impairment |
Solifenacin Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Overactive Bladder | 5 mg once daily | 5 mg to 10 mg once daily, based on response and tolerability | Swallow tablet whole with water. May be taken with or without food. |
