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Sotalol (Generic)
| Betapace Sotalol Hydrochloride | ||||||
Shipped from United Kingdom | ||||||
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General Medication Fact Sheet for Sotalol
| Field | Information |
|---|---|
| Generic Name | Sotalol |
| Brand Name Versions | Betapace, Sotylize, Sorine |
| Boxed/Label Warning | Initiation of sotalol, and dose increases, should be performed in a facility that can provide continuous ECG monitoring and has personnel trained in the treatment of life-threatening ventricular arrhythmias. Proarrhythmic effects can occur, especially with higher doses. |
| Purpose | Used to treat and prevent irregular heartbeats (arrhythmias) |
| Mechanism of Action | Blocks potassium channels, prolonging the action potential duration and refractoriness in cardiac tissue. Also has beta-adrenergic blocking properties. |
| Dosage Forms | Oral tablets |
| Available Strengths | 80 mg, 120 mg, 160 mg |
| Dosage Frequency | Typically twice daily, or as directed by a healthcare provider |
| Common Side Effects | Fatigue, dizziness, lightheadedness, slow heartbeat, shortness of breath |
| Serious Side Effects | New or worsening arrhythmias, prolonged QT interval, heart failure, bronchospasm, low blood pressure |
| Drug Interactions | Other antiarrhythmics, calcium channel blockers (e.g., verapamil, diltiazem), digoxin, diuretics (e.g., furosemide), certain antidepressants, some antihistamines |
| Important Notes | Do not stop taking suddenly without consulting your doctor. Regular ECG monitoring is important. Use caution when driving or operating machinery. |
| Storage | Store at room temperature away from moisture and light |
| Missed Dose | Take as soon as you remember unless it is almost time for your next dose. Do not double the dose. |
| Alternatives | Amiodarone, Flecainide, Propafenone, Metoprolol, Atenolol |
Sotalol Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Amiodarone (Cordarone, Pacerone) | Potassium, sodium, and calcium channel blocker; beta-adrenergic blocker | Broad-spectrum antiarrhythmic with significant side effects; often reserved for severe arrhythmias. |
| Flecainide (Tambocor) | Sodium channel blocker | Used for supraventricular arrhythmias; can be proarrhythmic in some patients. |
| Propafenone (Rythmol) | Sodium channel blocker with some beta-blocking activity | Used for supraventricular arrhythmias. |
| Metoprolol (Lopressor, Toprol XL) | Selective beta-1 adrenergic blocker | Primarily used for rate control in atrial fibrillation and other supraventricular tachycardias. |
| Atenolol (Tenormin) | Selective beta-1 adrenergic blocker | Similar to Metoprolol; primarily used for rate control. |
Sotalol Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Fatigue | New or worsening arrhythmias |
| Dizziness | Prolonged QT interval |
| Lightheadedness | Heart failure |
| Slow heartbeat | Bronchospasm |
| Shortness of breath | Low blood pressure (hypotension) |
Sotalol Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Ventricular Arrhythmias | 80 mg twice daily | 160-320 mg daily in divided doses | Initiation and dose increases require ECG monitoring. |
| Atrial Fibrillation/Flutter | 80 mg twice daily | 120-160 mg twice daily | Dosage adjusted based on renal function and response. |
Sotalol Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $5 |
| Without Insurance (U.S.) | $20 |
| From CPS | $18 |
