Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
General Medication Fact Sheet for Sovaldi
| Field | Information |
|---|---|
| Medication Name | Sovaldi |
| Generic Name | Sofosbuvir |
| Boxed/Label Warning | Hepatitis B virus reactivation in patients co-infected with HBV and HCV. Test all patients for HBV infection before initiating treatment. |
| Purpose | Antiviral medication used to treat chronic hepatitis C virus (HCV) infection |
| Mechanism of Action | Inhibits the HCV NS5B RNA-dependent RNA polymerase, which is essential for viral replication |
| Dosage Forms | Oral tablets |
| Available Strengths | 400 mg |
| Dosage Frequency | Once daily |
| Common Side Effects | Fatigue, headache, nausea, insomnia |
| Serious Side Effects | Hepatitis B reactivation, slowed heart rate (bradycardia) when used with amiodarone |
| Drug Interactions | Amiodarone, rifampin, St. John’s Wort, carbamazepine, phenytoin, oxcarbazepine |
| Important Notes | Must be used in combination with other antiviral medications; do not use as monotherapy. |
| Storage | Store at room temperature away from moisture and light |
| Missed Dose | Take as soon as you remember on the same day; do not double the dose |
| Alternatives | Epclusa (sofosbuvir/velpatasvir), Harvoni (ledipasvir/sofosbuvir), Mavyret (glecaprevir/pibrentasvir), Vosevi (sofosbuvir/velpatasvir/voxilaprevir) |
Sovaldi Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Epclusa (sofosbuvir/velpatasvir) | Inhibits HCV NS5B polymerase and NS5A | Combination drug effective against all HCV genotypes. |
| Harvoni (ledipasvir/sofosbuvir) | Inhibits HCV NS5A and NS5B polymerase | Combination drug effective against certain HCV genotypes. |
| Mavyret (glecaprevir/pibrentasvir) | Inhibits HCV NS3/4A protease and NS5A | Combination drug effective against all HCV genotypes. |
| Vosevi (sofosbuvir/velpatasvir/voxilaprevir) | Inhibits HCV NS5B polymerase, NS5A, and NS3/4A protease | Combination drug used for patients who have failed previous HCV treatment. |
Sovaldi Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Fatigue | Hepatitis B virus reactivation |
| Headache | Slowed heart rate (bradycardia) when used with amiodarone |
| Nausea | Allergic reactions (rare) |
Sovaldi Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Chronic Hepatitis C Virus (HCV) Infection | 400 mg | 400 mg once daily | Must be used in combination with other antiviral medications. Follow your doctor’s instructions precisely. |
Sovaldi Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $50 |
| Without Insurance (U.S.) | $28,000 |
| From CPS | $21,000 |
