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General Medication Fact Sheet for Sparfloxacin
| Field | Information |
|---|---|
| Medication Name | Sparfloxacin |
| Generic Name | Sparfloxacin |
| Boxed/Label Warning | Fluoroquinolones, including Sparfloxacin, are associated with an increased risk of tendinitis and tendon rupture in all ages. This risk is further increased in older patients, patients taking corticosteroids, and in patients with kidney, heart, or lung transplants. Discontinue Sparfloxacin immediately if the patient experiences pain, swelling, inflammation of a tendon, or rupture of a tendon. Avoid use of fluoroquinolones in patients who have experienced any of these serious adverse reactions associated with fluoroquinolones. |
| Purpose | Antibiotic used to treat bacterial infections. |
| Mechanism of Action | Inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication and repair. |
| Dosage Forms | Oral tablets |
| Available Strengths | 200 mg |
| Dosage Frequency | Typically once daily, or as directed by a healthcare provider. |
| Common Side Effects | Nausea, headache, dizziness, diarrhea, photosensitivity. |
| Serious Side Effects | Tendon rupture, peripheral neuropathy, QT prolongation, central nervous system effects (e.g., seizures), severe allergic reactions. |
| Drug Interactions | Antacids containing aluminum or magnesium, iron supplements, sucralfate, warfarin, certain antiarrhythmic drugs (e.g., amiodarone). |
| Important Notes | Avoid prolonged sun exposure due to increased photosensitivity; consult a doctor if you have a history of seizures, heart problems, or tendon problems. Discontinue immediately if tendon pain or swelling occurs. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Ciprofloxacin, Levofloxacin, Moxifloxacin, Azithromycin, Doxycycline. |
Sparfloxacin Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Ciprofloxacin (Cipro) | Inhibits bacterial DNA gyrase and topoisomerase IV | Another fluoroquinolone, effective against a broad range of bacteria. |
| Levofloxacin (Levaquin) | Inhibits bacterial DNA gyrase and topoisomerase IV | Also a fluoroquinolone with a broad spectrum of activity. |
| Moxifloxacin (Avelox) | Inhibits bacterial DNA gyrase and topoisomerase IV | A fluoroquinolone used for respiratory and skin infections. |
| Azithromycin (Zithromax) | Macrolide antibiotic; inhibits bacterial protein synthesis | Used for various respiratory and skin infections; different mechanism of action than fluoroquinolones. |
| Doxycycline (Vibramycin) | Tetracycline antibiotic; inhibits bacterial protein synthesis | Used for a variety of infections, including respiratory, skin, and tick-borne illnesses. |
Sparfloxacin Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Nausea | Tendon rupture |
| Headache | Peripheral neuropathy (nerve damage) |
| Dizziness | QT prolongation (heart rhythm issues) |
| Diarrhea | Central nervous system effects (seizures, psychosis) |
| Photosensitivity (increased sensitivity to sunlight) | Severe allergic reactions (rash, itching, swelling, difficulty breathing) |
| Insomnia | Liver damage |
Sparfloxacin Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Bacterial Infections (General) | 400 mg | 200 mg daily for 10-14 days, depending on infection | Take on an empty stomach or with food; avoid antacids containing aluminum or magnesium within 2 hours of taking Sparfloxacin. |
| Community-Acquired Pneumonia | 400 mg | 200 mg daily for 10 days | Take on an empty stomach or with food; avoid antacids containing aluminum or magnesium within 2 hours of taking Sparfloxacin. |
| Acute Bacterial Sinusitis | 400 mg | 200 mg daily for 10 days | Take on an empty stomach or with food; avoid antacids containing aluminum or magnesium within 2 hours of taking Sparfloxacin. |
Sparfloxacin Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $25 |
| Without Insurance (U.S.) | $80 |
| From Canada | $45.35 |
