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Stimate Nasal Spray (Desmopressin Acetate)
| Desmopressin Nasal Spray (Generic) Desmopressin Acetate | ||||||
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Shipped from Canada | ||||||
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| Select product strength & quantity:
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| Desmopressin Nasal Spray (Generic) Desmopressin Acetate | ||||||
Shipped from United Kingdom | ||||||
| | ||||||
| Select product strength & quantity:
Who is the product for? YouOtherAdd Family Member/PetYou must be logged in to add additional members to the order. Don't have an account? or Add Family Member/PetSign inTo continue, please enter your email address and password that you use for your account. | ||||||
General Medication Fact Sheet for Stimate Nasal Spray
| Field | Information |
|---|---|
| Medication Name | Stimate Nasal Spray |
| Generic Name | Desmopressin Acetate |
| Purpose | Treatment of primary nocturnal enuresis (bedwetting), hemophilia A, and von Willebrand’s disease. |
| Mechanism of Action | Synthetic analogue of vasopressin (antidiuretic hormone); increases plasma levels of factor VIII and von Willebrand factor. |
| Dosage Forms | Nasal Spray |
| Available Strengths | 1.5 mg/mL (150 mcg per spray) |
| Dosage Frequency | Varies depending on the condition being treated; typically once daily at bedtime for bedwetting. |
| Common Side Effects | Nasal congestion, headache, nausea, nosebleeds, flushing. |
| Serious Side Effects | Hyponatremia (low sodium levels), seizures, allergic reactions, water intoxication. |
| Drug Interactions | Tricyclic antidepressants, selective serotonin reuptake inhibitors (SSRIs), chlorpromazine, carbamazepine, NSAIDs. |
| Important Notes | Fluid intake should be carefully monitored to avoid water intoxication and hyponatremia. Consult a healthcare provider if you experience signs of hyponatremia (e.g., headache, nausea, confusion). |
| Storage | Store in the refrigerator (2-8°C or 36-46°F). Protect from light. |
| Missed Dose | If you miss a dose, take it as soon as you remember unless it is almost time for your next dose. Do not double the dose. |
| Alternatives | DDAVP Tablets (desmopressin), Tofranil (imipramine), Oxybutynin. |
Stimate Nasal Spray Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| DDAVP Tablets (desmopressin) | Synthetic analogue of vasopressin (antidiuretic hormone) | Oral form of desmopressin, used for similar indications. |
| Tofranil (imipramine) | Tricyclic antidepressant | Used off-label for nocturnal enuresis, especially when desmopressin is not effective. |
| Oxybutynin | Anticholinergic, antispasmodic | Can be used off-label for nocturnal enuresis by reducing bladder contractions. |
Stimate Nasal Spray Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Nasal congestion | Hyponatremia (low sodium levels) |
| Headache | Seizures |
| Nausea | Allergic reactions (rash, itching, swelling, difficulty breathing) |
| Nosebleeds | Water intoxication |
| Flushing | Severe headache or confusion |
Stimate Nasal Spray Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Primary Nocturnal Enuresis (Bedwetting) | 20 mcg (0.2 mL) | 20 mcg (0.2 mL) at bedtime | Administer one hour before bedtime. Limit fluid intake from 1 hour before until 8 hours after administration. |
| Hemophilia A (Mild to Moderate) | Dosage determined by physician | Dosage determined by physician | Administer under medical supervision. Monitor factor VIII levels. |
| von Willebrand’s Disease (Type I) | Dosage determined by physician | Dosage determined by physician | Administer under medical supervision. Monitor von Willebrand factor levels. |
