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Sulfasalazine (Generic)
| Salazopyrin EN Sulfasalazine | ||||||
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Shipped from Canada | ||||||
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| Salazopyrin EN Sulfasalazine | ||||||
|
Shipped from Canada | ||||||
| | ||||||
| Select product strength & quantity:
Who is the product for? YouOtherAdd Family Member/PetYou must be logged in to add additional members to the order. Don't have an account? or Add Family Member/PetSign inTo continue, please enter your email address and password that you use for your account. | ||||||
General Medication Fact Sheet for Sulfasalazine
| Field | Information |
|---|---|
| Generic Name | Sulfasalazine |
| Brand Name Versions | Azulfidine, Sulfazine |
| Boxed/Label Warning | May cause serious infections, blood disorders, or severe allergic reactions. |
| Purpose | Used to treat ulcerative colitis, rheumatoid arthritis, and other inflammatory conditions. |
| Mechanism of Action | Modulates inflammatory responses by affecting various mediators and immune cells. |
| Dosage Forms | Oral tablets, enteric-coated tablets |
| Available Strengths | 500 mg |
| Dosage Frequency | Typically two to four times daily, as directed by a healthcare provider. |
| Common Side Effects | Nausea, vomiting, loss of appetite, headache, skin rash. |
| Serious Side Effects | Blood disorders, liver problems, severe skin reactions, allergic reactions. |
| Drug Interactions | Iron supplements, antibiotics (e.g., digoxin), methotrexate, Azathioprine. |
| Important Notes | Take with food and plenty of water. Regular blood tests are needed to monitor for side effects. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Mesalamine, Corticosteroids, Azathioprine, Infliximab |
Sulfasalazine Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Mesalamine | Anti-inflammatory; reduces inflammation in the colon. | Often used as a first-line treatment for ulcerative colitis. |
| Corticosteroids (Prednisone) | Immune suppression; reduces inflammation. | Used for short-term management of severe inflammation. |
| Azathioprine | Immunosuppressant; reduces the activity of the immune system. | Used as a steroid-sparing agent in ulcerative colitis. |
| Infliximab (Remicade) | TNF-alpha inhibitor; blocks the action of TNF-alpha, a protein involved in inflammation. | Biologic medication used for moderate to severe ulcerative colitis. |
Sulfasalazine Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Nausea | Blood disorders (e.g., anemia, leukopenia) |
| Vomiting | Liver problems |
| Loss of appetite | Severe skin reactions (e.g., Stevens-Johnson syndrome) |
| Headache | Allergic reactions (rash, itching, swelling, difficulty breathing) |
| Skin rash | Lung problems (e.g., pneumonitis) |
Sulfasalazine Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Ulcerative Colitis | 1-2 grams per day | 2-4 grams per day in divided doses | Take with food and plenty of water. |
| Rheumatoid Arthritis | 0.5-1 gram per day | 2 grams per day in divided doses | May take several weeks to see improvement. |
