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Taclonex (Betamethasone , Calcipotriene)
| Betamethasone/Calcipotriene Ointment (Generic) Betamethasone Dipropionate, Calcipotriene | ||||||
Shipped from United Kingdom | ||||||
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General Medication Fact Sheet for Taclonex
| Field | Information |
|---|---|
| Medication Name | Taclonex |
| Generic Name | Calcipotriene and Betamethasone Dipropionate |
| Boxed/Label Warning | Prolonged use may suppress the hypothalamic-pituitary-adrenal (HPA) axis, cause Cushing’s syndrome, hyperglycemia, and glucosuria. Topical calcipotriene can cause hypercalcemia or hypercalciuria. |
| Purpose | Treatment of plaque psoriasis of the scalp and body. |
| Mechanism of Action | Calcipotriene is a vitamin D3 analog that inhibits keratinocyte proliferation and promotes differentiation. Betamethasone dipropionate is a corticosteroid that reduces inflammation. |
| Dosage Forms | Topical ointment and topical suspension |
| Available Strengths | Calcipotriene 0.005% and Betamethasone Dipropionate 0.064% |
| Dosage Frequency | Apply to affected areas once daily for up to 4 weeks. |
| Common Side Effects | Burning, itching, irritation, folliculitis, skin atrophy. |
| Serious Side Effects | Hypercalcemia, HPA axis suppression, Cushing’s syndrome, hyperglycemia, allergic contact dermatitis, skin discoloration. |
| Drug Interactions | Other topical corticosteroids, drugs affecting calcium levels (e.g., thiazide diuretics, calcium supplements). |
| Important Notes | Avoid use on the face, groin, or axillae unless directed by a physician. Wash hands after application. Do not use with occlusive dressings. Monitor for signs of hypercalcemia or HPA axis suppression with prolonged use. |
| Storage | Store at room temperature away from heat and direct light. |
| Missed Dose | Apply as soon as you remember. If it is almost time for your next application, skip the missed dose and apply the next dose at the regularly scheduled time. Do not apply a double dose to make up for a missed one. |
| Alternatives | Enstilar (calcipotriene and betamethasone), Dovonex (calcipotriene), Temovate (clobetasol propionate), calcitriol |
Taclonex Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Enstilar (calcipotriene and betamethasone) | Vitamin D analog and corticosteroid combination | Similar combination product, available as a foam. |
| Dovonex (calcipotriene) | Vitamin D analog | Available as a cream, ointment, and solution. May be used alone or in combination with a topical corticosteroid. |
| Temovate (clobetasol propionate) | High-potency topical corticosteroid | Effective for reducing inflammation and itching, but carries a higher risk of side effects with prolonged use. |
| calcitriol | Vitamin D analog | Available as a topical ointment. May be less potent than calcipotriene. |
Taclonex Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Burning | Hypercalcemia |
| Itching | HPA axis suppression |
| Irritation | Cushing’s syndrome |
| Folliculitis | Hyperglycemia |
| Skin atrophy | Allergic contact dermatitis |
| Dry skin | Skin Discoloration |
Taclonex Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Plaque Psoriasis (Scalp) | Apply a thin layer to the affected areas once daily | Once daily application for up to 4 weeks | Do not exceed 60 grams of ointment per week. |
| Plaque Psoriasis (Body) | Apply a thin layer to the affected areas once daily | Once daily application for up to 4 weeks | Do not exceed 60 grams of ointment per week. |
Taclonex Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $60 |
| Without Insurance (U.S.) | $350 |
| From CPS | $60 |
