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General Medication Fact Sheet for Tarka
| Field | Information |
|---|---|
| Medication Name | Tarka |
| Generic Name | Trandolapril/Verapamil |
| Purpose | Treatment of hypertension (high blood pressure) |
| Mechanism of Action | Combines an ACE inhibitor (trandolapril) and a calcium channel blocker (verapamil) to lower blood pressure. Trandolapril inhibits the angiotensin-converting enzyme, reducing the production of angiotensin II, a vasoconstrictor. Verapamil blocks calcium channels, relaxing blood vessels. |
| Dosage Forms | Oral tablets |
| Available Strengths | 1 mg/240 mg, 2 mg/180 mg, 2 mg/240 mg, 4 mg/240 mg |
| Dosage Frequency | Once daily, or as directed by a healthcare provider |
| Common Side Effects | Cough, headache, dizziness, fatigue, constipation, peripheral edema (swelling in ankles and feet) |
| Serious Side Effects | Hypotension (low blood pressure), angioedema (swelling of the face, lips, tongue, or throat), hyperkalemia (high potassium levels), bradycardia (slow heart rate), heart failure, liver problems |
| Drug Interactions | Other antihypertensives, digoxin, certain antiarrhythmics (e.g., quinidine), beta-blockers, statins, CYP3A4 inhibitors, NSAIDs, alcohol |
| Important Notes | Monitor blood pressure regularly. Avoid grapefruit juice, as it can increase verapamil levels. Use caution when driving or operating machinery due to dizziness. Inform your doctor if you are pregnant or breastfeeding. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose. |
| Alternatives | Lisinopril, Amlodipine, Metoprolol, Hydrochlorothiazide |
Tarka Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Lisinopril (Prinivil, Zestril) | ACE inhibitor | Inhibits the angiotensin-converting enzyme, reducing the production of angiotensin II. |
| Amlodipine (Norvasc) | Calcium channel blocker | Relaxes and widens blood vessels, making it easier for the heart to pump blood. |
| Metoprolol (Lopressor, Toprol XL) | Beta-blocker | Blocks the effects of epinephrine (adrenaline), slowing down the heart rate and reducing blood pressure. |
| Hydrochlorothiazide (Microzide) | Thiazide diuretic | Helps the body get rid of extra salt and water, which helps lower blood pressure. |
Tarka Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Cough | Hypotension (low blood pressure) |
| Headache | Angioedema (swelling of the face, lips, tongue, or throat) |
| Dizziness | Hyperkalemia (high potassium levels) |
| Fatigue | Bradycardia (slow heart rate) |
| Constipation | Heart failure |
| Peripheral edema (swelling in ankles and feet) | Liver problems |
Tarka Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Hypertension | 1 mg/240 mg once daily | May be increased to 2 mg/240 mg or 4 mg/240 mg once daily, as directed by your doctor. | Take at the same time each day. Swallow whole; do not crush or chew. |
Tarka Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $20 |
| Without Insurance (U.S.) | $150 |
| From CPS | $36 |
