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General Medication Fact Sheet for Tobradex
| Field | Information |
|---|---|
| Medication Name | Tobradex |
| Generic Name | Tobramycin/Dexamethasone |
| Boxed/Label Warning | Prolonged use may result in glaucoma, with damage to the optic nerve, defects in visual acuity and fields of vision, and posterior subcapsular cataract formation. Prolonged use may also suppress the host response and thus increase the hazard of secondary ocular infections. |
| Purpose | Treatment of bacterial infections of the eye with associated inflammation. |
| Mechanism of Action | Tobramycin is an aminoglycoside antibiotic that inhibits bacterial protein synthesis. Dexamethasone is a corticosteroid that reduces inflammation. |
| Dosage Forms | Ophthalmic suspension (eye drops), ophthalmic ointment |
| Available Strengths | Tobramycin 0.3% / Dexamethasone 0.1% |
| Dosage Frequency | Typically, 1-2 drops every 4-6 hours. During the initial 24-48 hours, the dosage may be increased to 1-2 drops every 2 hours. |
| Common Side Effects | Eye itching, redness, burning, stinging, discomfort, blurred vision, eyelid itching or swelling. |
| Serious Side Effects | Severe eye pain, vision changes, signs of a new eye infection (discharge, persistent redness), increased pressure in the eye. |
| Drug Interactions | Systemic absorption of topical corticosteroids may increase if excessive doses or prolonged treatment is used, potentially interacting with systemic medications. Concurrent use with NSAIDs may increase the risk of corneal healing problems. |
| Important Notes | Do not use with contact lenses. If symptoms do not improve after two days, consult a doctor. Prolonged use may lead to glaucoma, cataract formation, or secondary infections. Use with caution in patients with a history of herpes simplex virus infection. |
| Storage | Store at room temperature away from moisture and light. Keep the bottle tightly closed. |
| Missed Dose | Apply the drops as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not double the dose to catch up. |
| Alternatives | Pred Forte (prednisolone acetate), Ciloxan (ciprofloxacin), Erythromycin ophthalmic ointment, Azasite (azithromycin) |
Tobradex Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Pred Forte (prednisolone acetate) | Corticosteroid, reduces inflammation | Used for inflammation, but does not treat infection. |
| Ciloxan (ciprofloxacin) | Quinolone antibiotic, inhibits bacterial DNA replication | Antibiotic eye drop, treats bacterial infections. |
| Erythromycin ophthalmic ointment | Macrolide antibiotic, inhibits bacterial protein synthesis | Antibiotic eye ointment, treats bacterial infections, often used in newborns. |
| Azasite (azithromycin) | Macrolide antibiotic, inhibits bacterial protein synthesis | Antibiotic eye drop, treats bacterial infections. |
Tobradex Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Eye itching | Severe eye pain |
| Eye redness | Vision changes |
| Burning or stinging | Signs of new eye infection (discharge, persistent redness) |
| Blurred vision | Increased pressure in the eye (glaucoma) |
| Eyelid itching or swelling | Cataract formation |
Tobradex Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Bacterial eye infection with inflammation (Ophthalmic Suspension) | 1-2 drops every 4-6 hours | 1-2 drops every 4-6 hours | Shake well before use. During the initial 24-48 hours, the dosage may be increased to 1-2 drops every 2 hours. |
| Bacterial eye infection with inflammation (Ophthalmic Ointment) | Apply a thin ribbon into the conjunctival sac every 8-12 hours | Apply a thin ribbon into the conjunctival sac every 8-12 hours | Apply a thin ribbon into the conjunctival sac every 8-12 hours. |
Tobradex Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $35 |
| Without Insurance (U.S.) | $360 |
| From Canada | $27 |
