Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
Tofranil (Imipramine)
| Imipramine (Generic) Imipramine Hydrochloride | ||||||
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Shipped from Canada | ||||||
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| Imipramine (Generic) Imipramine Hydrochloride | ||||||
Shipped from United Kingdom | ||||||
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| Imipramine (Generic) Imipramine Hydrochloride | ||||||
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Shipped from Mauritius | ||||||
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Who is the product for? YouOtherAdd Family Member/PetYou must be logged in to add additional members to the order. Don't have an account? or Add Family Member/PetSign inTo continue, please enter your email address and password that you use for your account. | ||||||
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General Medication Fact Sheet for Tofranil
| Field | Information |
|---|---|
| Medication Name | Tofranil |
| Generic Name | Imipramine |
| Boxed/Label Warning | Increased risk of suicidal thoughts and behaviors in children, adolescents, and young adults. |
| Purpose | Treatment of depression, bedwetting (nocturnal enuresis) in children, and certain pain conditions. |
| Mechanism of Action | Blocks the reuptake of norepinephrine and serotonin in the brain, increasing the levels of these neurotransmitters. |
| Dosage Forms | Oral tablets |
| Available Strengths | 10 mg, 25 mg, 50 mg, 75 mg, 100 mg, 125 mg, 150 mg |
| Dosage Frequency | Typically 1 to 4 times daily, as directed by a healthcare provider. |
| Common Side Effects | Dry mouth, constipation, blurred vision, dizziness, drowsiness, weight gain, increased appetite. |
| Serious Side Effects | Suicidal thoughts, irregular heartbeat, seizures, mania, confusion, difficulty urinating, severe constipation. |
| Drug Interactions | MAO inhibitors, SSRIs, SNRIs, antiarrhythmics, anticholinergics, certain blood pressure medications, alcohol. |
| Important Notes | Do not stop taking suddenly; may cause withdrawal symptoms. Use caution when driving or operating machinery. Inform your doctor of all medications and supplements you are taking. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Sertraline (Zoloft), Fluoxetine (Prozac), Amitriptyline, Nortriptyline (Pamelor). |
Tofranil Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Sertraline (Zoloft) | Selective serotonin reuptake inhibitor (SSRI) | Often a first-line treatment for depression. |
| Fluoxetine (Prozac) | Selective serotonin reuptake inhibitor (SSRI) | Another commonly prescribed SSRI for depression. |
| Amitriptyline | Tricyclic antidepressant (TCA) | Similar mechanism of action to Tofranil but may have a different side effect profile. |
| Nortriptyline (Pamelor) | Tricyclic antidepressant (TCA) | Another TCA with a similar mechanism of action to Tofranil. |
Tofranil Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Dry mouth | Suicidal thoughts |
| Constipation | Irregular heartbeat |
| Blurred vision | Seizures |
| Dizziness | Mania |
| Drowsiness | Confusion |
| Weight gain | Difficulty urinating |
| Increased appetite | Severe Constipation |
Tofranil Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Depression (Adults) | 25 mg 1-3 times daily | 50-150 mg daily, divided doses | May increase gradually as needed. |
| Nocturnal Enuresis (Children) | 25 mg at bedtime | 25-75 mg at bedtime | Dose depends on weight; administer 1 hour before bedtime. |
| Pain Management | 10-25 mg at bedtime | 25-75 mg daily, divided doses | May take several weeks to see effect. |
Tofranil Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $25 |
| Without Insurance (U.S.) | $37 |
| From CPS | $15 |
