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General Medication Fact Sheet for Toradol Injection
| Field | Information |
|---|---|
| Medication Name | Toradol Injection |
| Generic Name | Ketorolac Tromethamine |
| Boxed/Label Warning | Serious cardiovascular and gastrointestinal events, renal effects, bleeding risk, and should not be used for chronic pain. |
| Purpose | Short-term management of moderately severe acute pain that requires analgesia at the opioid level. |
| Mechanism of Action | Inhibits prostaglandin synthesis by decreasing the activity of cyclooxygenase (COX) enzymes. |
| Dosage Forms | Injectable solution |
| Available Strengths | 15 mg/mL, 30 mg/mL |
| Dosage Frequency | Every 6 hours as needed, not to exceed 5 days of treatment. |
| Common Side Effects | Drowsiness, dizziness, headache, nausea, injection site pain. |
| Serious Side Effects | Gastrointestinal bleeding, kidney damage, heart attack, stroke, allergic reactions (anaphylaxis). |
| Drug Interactions | NSAIDs (e.g., ibuprofen, Naproxen), anticoagulants (e.g., warfarin), aspirin, selective serotonin reuptake inhibitors (SSRIs), ACE inhibitors, diuretics, probenecid, methotrexate. |
| Important Notes | Use the lowest effective dose for the shortest duration consistent with individual patient treatment goals. Not for chronic use. Avoid in patients with renal impairment, GI ulcers or bleeding, or cardiovascular disease. |
| Storage | Store at controlled room temperature (20-25°C or 68-77°F). Protect from light. |
| Missed Dose | This medication is administered by a healthcare professional; a missed dose is unlikely. |
| Alternatives | Ibuprofen, Naproxen, Morphine, Hydromorphone |
Toradol Injection Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Ibuprofen (Advil, Motrin) | Non-selective COX inhibitor | Oral NSAID for mild to moderate pain; less potent than ketorolac. |
| Naproxen (Aleve) | Non-selective COX inhibitor | Oral NSAID with a longer duration of action than ibuprofen. |
| Morphine | Opioid receptor agonist | Strong opioid analgesic; reserved for severe pain. |
| Hydromorphone (Dilaudid) | Opioid receptor agonist | Potent opioid analgesic; alternative for severe pain when other options are not suitable. |
Toradol Injection Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Drowsiness | Gastrointestinal bleeding |
| Dizziness | Kidney damage |
| Headache | Heart attack |
| Nausea | Stroke |
| Injection site pain | Allergic reactions (rash, itching, swelling, difficulty breathing) |
Toradol Injection Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Acute Pain (adults < 65 years) | 30 mg IV or 60 mg IM (single dose) OR 15 mg IV or 30 mg IM (every 6 hours) | Not applicable; single dose or short-term use only | Use the lowest effective dose. IM injection should be given slowly and deeply into the muscle. Do not exceed 5 days of treatment. |
| Acute Pain (adults ≥ 65 years, renally impaired, or weight < 50 kg) | 15 mg IV or 30 mg IM (single dose) OR 15 mg IV or 15 mg IM (every 6 hours) | Not applicable; single dose or short-term use only | Dosage should be adjusted based on the patient’s condition and response. Monitor renal function. Do not exceed 5 days of treatment. |
Toradol Injection Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $70 |
| Without Insurance (U.S.) | $95 – $163 |
| From Canada | $26 |
