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Torsemide (Generic)
| Demadex Torsemide | ||||||
Shipped from United Kingdom | ||||||
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General Medication Fact Sheet for Torsemide
| Field | Information |
|---|---|
| Generic Name | Torsemide |
| Brand Name Versions | Demadex |
| Purpose | Loop diuretic used to treat edema associated with heart failure, kidney disease, or liver disease, and to treat hypertension. |
| Mechanism of Action | Inhibits the Na+/K+/2Cl- cotransporter in the loop of Henle, reducing sodium and chloride reabsorption and increasing water excretion. |
| Dosage Forms | Oral tablets |
| Available Strengths | 5 mg, 10 mg, 20 mg, 100 mg |
| Dosage Frequency | Typically once daily, or as directed by a healthcare provider. |
| Common Side Effects | Frequent urination, dizziness, headache, diarrhea, constipation. |
| Serious Side Effects | Electrolyte imbalances (e.g., low potassium, low sodium), dehydration, kidney problems, muscle cramps, hearing loss. |
| Drug Interactions | Digoxin, aminoglycoside antibiotics, lithium, NSAIDs, ACE inhibitors, ARBs, corticosteroids. |
| Important Notes | Monitor electrolyte levels regularly, especially potassium. Use caution when standing up to avoid dizziness. Consult a doctor if you experience muscle cramps, weakness, or irregular heartbeat. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Furosemide, Bumetanide, Hydrochlorothiazide, Spironolactone |
Torsemide Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Furosemide (Lasix) | Loop diuretic; inhibits Na+/K+/2Cl- cotransporter | Another commonly used loop diuretic. |
| Bumetanide (Bumex) | Loop diuretic; inhibits Na+/K+/2Cl- cotransporter | More potent than Furosemide. |
| Hydrochlorothiazide (Microzide) | Thiazide diuretic; inhibits Na+/Cl- cotransporter in the distal convoluted tubule | Less potent than loop diuretics; often used for hypertension. |
| Spironolactone (Aldactone) | Potassium-sparing diuretic; aldosterone antagonist | Helps retain potassium; often used in combination with other diuretics. |
Torsemide Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Frequent urination | Electrolyte imbalances (low potassium, low sodium) |
| Dizziness | Dehydration |
| Headache | Kidney problems |
| Diarrhea | Muscle cramps |
| Constipation | Hearing loss |
Torsemide Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Edema associated with heart failure | 10-20 mg daily | Adjusted based on response, up to 200 mg daily. | May be taken with or without food. |
| Edema associated with kidney disease | 20 mg daily | Adjusted based on response, up to 200 mg daily. | May be taken with or without food. |
| Hypertension | 5 mg daily | May be increased to 10 mg daily if needed. | May be taken with or without food. |
