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Trazodone (Generic)
| Desyrel Trazodone Hydrochloride | ||||||
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Shipped from Mauritius | ||||||
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| Select product strength & quantity:
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General Medication Fact Sheet for Trazodone
| Field | Information |
|---|---|
| Generic Name | Trazodone |
| Brand Name Versions | Desyrel, Oleptro |
| Boxed/Label Warning | Antidepressants may increase the risk of suicidal thoughts and behavior in children, adolescents, and young adults. |
| Purpose | Antidepressant and sleep aid |
| Mechanism of Action | Serotonin antagonist and reuptake inhibitor (SARI) |
| Dosage Forms | Oral tablets |
| Available Strengths | 50 mg, 100 mg, 150 mg, 300 mg |
| Dosage Frequency | Typically once or twice daily, as directed by a healthcare provider |
| Common Side Effects | Drowsiness, dizziness, dry mouth, blurred vision |
| Serious Side Effects | Irregular heartbeat, suicidal thoughts, serotonin syndrome, priapism |
| Drug Interactions | Other antidepressants (SSRIs, SNRIs, MAOIs), anticoagulants (e.g., warfarin), digoxin, ketoconazole |
| Important Notes | May cause drowsiness; use caution when driving or operating machinery. Avoid alcohol. |
| Storage | Store at room temperature away from moisture and light |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Mirtazapine, Sertraline, Amitriptyline, Doxepin |
Trazodone Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Mirtazapine (Remeron) | Alpha-2 adrenergic antagonist; enhances serotonin and norepinephrine neurotransmission | May cause weight gain and sedation. |
| Sertraline (Zoloft) | Selective serotonin reuptake inhibitor (SSRI) | Primarily used as an antidepressant; may also help with anxiety. |
| Amitriptyline (Elavil) | Tricyclic antidepressant (TCA) | Older antidepressant with more potential side effects. |
| Doxepin (Silenor) | Tricyclic antidepressant (TCA) | Can be used for insomnia at lower doses. |
Trazodone Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Drowsiness | Irregular heartbeat |
| Dizziness | Suicidal thoughts |
| Dry mouth | Serotonin syndrome |
| Blurred vision | Priapism (prolonged erection) |
| Constipation | Orthostatic hypotension (dizziness upon standing) |
Trazodone Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Depression | 50-150 mg | 150-300 mg daily, divided doses | Take after a meal or light snack. |
| Insomnia | 25-50 mg | 25-100 mg at bedtime | Take at bedtime; adjust dose based on response. |
