Tremfya (Guselkumab)

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Description

General Medication Fact Sheet for Tremfya

Field Information
Medication Name Tremfya
Generic Name Guselkumab
Purpose Treatment of moderate to severe plaque psoriasis and active psoriatic arthritis.
Mechanism of Action Selective interleukin-23 (IL-23) inhibitor. It binds to the p19 subunit of IL-23, preventing it from binding to its receptor and inhibiting the release of pro-inflammatory cytokines.
Dosage Forms Subcutaneous injection
Available Strengths 100 mg/mL
Dosage Frequency Initially, two injections 4 weeks apart, followed by one injection every 8 weeks.
Common Side Effects Upper respiratory infections, headache, injection site reactions, joint pain, diarrhea, gastroenteritis, tinea infections.
Serious Side Effects Serious infections (bacterial, fungal, or viral), allergic reactions (hives, difficulty breathing, swelling of face, lips, tongue, or throat), tuberculosis (TB) reactivation.
Drug Interactions Live vaccines (avoid), CYP450 substrates (potential interaction due to altered cytokine levels).
Important Notes Inform your doctor if you have an infection, are planning to receive any vaccinations, or have a history of tuberculosis. Evaluate for TB infection prior to initiating treatment.
Storage Store in the refrigerator at 2°C to 8°C (36°F to 46°F) in the original carton to protect from light. Do not freeze. If necessary, Tremfya may be stored at room temperature up to 30°C (86°F) for a single period of up to 30 days. Once stored at room temperature, do not return to refrigerator; discard if not used within 30 days.
Missed Dose Administer the injection as soon as you remember, then continue with your regular schedule. Contact your healthcare provider for guidance.
Alternatives Cosentyx (secukinumab), Stelara (ustekinumab), Skyrizi (risankizumab), Enbrel (etanercept)

Tremfya Alternatives

Medication Mechanism of Action Notes
Cosentyx (secukinumab) IL-17A inhibitor Another biologic used for plaque psoriasis and psoriatic arthritis.
Stelara (ustekinumab) IL-12 and IL-23 inhibitor Biologic option for psoriasis and psoriatic arthritis; targets different interleukins than Tremfya.
Skyrizi (risankizumab) IL-23 inhibitor Similar mechanism of action to Tremfya.
Enbrel (etanercept) TNF-alpha inhibitor A different class of biologic that can be used for psoriatic arthritis and psoriasis.

Tremfya Side Effects

Common Side Effects Serious Side Effects
Upper respiratory infections Serious infections (bacterial, fungal, viral)
Headache Allergic reactions (hives, difficulty breathing, swelling)
Injection site reactions (redness, pain, swelling) Tuberculosis (TB) reactivation
Joint Pain New or worsening inflammatory bowel disease (Crohn’s disease or ulcerative colitis)

Tremfya Dosage Guide

Condition Starting Dose Maintenance Dose Administration Notes
Plaque Psoriasis 100 mg 100 mg subcutaneously at weeks 0, 4, and every 8 weeks thereafter Administered by subcutaneous injection. Rotate injection sites with each dose.
Psoriatic Arthritis 100 mg 100 mg subcutaneously at weeks 0, 4, and every 8 weeks thereafter Administered by subcutaneous injection. Can be used alone or in combination with a DMARD.
Why Americans Buy Tremfya from Canada Pharmacy Store?

Why Americans Buy Tremfya from Canada Pharmacy Store?

Americans have trouble affording Tremfya due to numerous factors—but at Canada Pharmacy Store, we offer a safe, affordable alternative. That’s why thousands of Americans trust us to fill their prescriptions with real savings and real service.
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Our customers save up to 80% on their Tremfya prescriptions compared to U.S. pharmacy prices by ordering through licensed Canadian and international pharmacies.
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How to Order Tremfya Online

How to Order Tremfya Online

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Select Your Prescribed Tremfya Dosage

Choose the strength and quantity as directed by your healthcare provider and add it to your cart.

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Proceed Through Secure Checkout

Follow the steps to complete your order and provide necessary shipping and payment details.

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Upload Your Tremfya Prescription

Submit a prescription from a licensed U.S. healthcare provider that matches your order.

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Our Guarantee When You Buy Tremfya Through Canada Pharmacy Store

At Canada Pharmacy Store, your safety and satisfaction are our top priorities. We supply only authentic, high-quality medications by working exclusively with licensed Canadian pharmacies and trusted international partners. Every order is filled in accordance with strict regulatory standards and includes medication that’s fully approved by Health Canada or other recognized health authorities such as the MHRA (UK), HSA (Singapore), and the Pharmacy Board of Mauritius.

The Tremfya you receive is the same active medication as what’s available in the U.S.—the only difference is the packaging, which reflects its country of origin. Our licensed healthcare professionals review each order carefully to ensure it matches your prescription exactly.
To get Tremfya at a lower price, simply place your order above or give us a call at 1-888-903-2240