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Tresiba (Insulin Degludec)
| Tresiba FlexTouch Insulin degludec | ||||||
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Shipped from Canada | ||||||
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General Medication Fact Sheet for Tresiba
| Field | Information |
|---|---|
| Medication Name | Tresiba |
| Generic Name | Insulin degludec |
| Boxed/Label Warning | There is no boxed warning for Tresiba. |
| Purpose | Long-acting insulin used to control blood sugar in adults with diabetes mellitus. |
| Mechanism of Action | Forms multi-hexamers upon subcutaneous injection, resulting in a depot of insulin degludec that is slowly and continuously absorbed into the circulation. |
| Dosage Forms | Solution for subcutaneous injection (FlexTouch pen, vial) |
| Available Strengths | 100 units/mL (U-100), 200 units/mL (U-200) |
| Dosage Frequency | Once daily |
| Common Side Effects | Hypoglycemia (low blood sugar), injection site reactions, weight gain, edema |
| Serious Side Effects | Severe hypoglycemia, allergic reactions (rash, itching, swelling, difficulty breathing), hypokalemia |
| Drug Interactions | Other antidiabetic agents (e.g., metformin, sulfonylureas), beta-blockers, ACE inhibitors, salicylates, alcohol, corticosteroids, thiazide diuretics |
| Important Notes | Monitor blood glucose levels regularly; rotate injection sites to prevent lipodystrophy; always consult your healthcare provider for individualized dosing and management. |
| Storage | Store unopened pens/vials in the refrigerator. Opened pens/vials can be stored at room temperature for a specific period (check product label). Protect from heat and light. |
| Missed Dose | Take the missed dose as soon as you remember, but do not double your next dose. Consult your healthcare provider. |
| Alternatives | Insulin glargine (Lantus, Toujeo), Insulin detemir (Levemir), Insulin lispro (Humalog), Insulin aspart (Novolog) |
Tresiba Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Insulin glargine (Lantus, Toujeo) | Long-acting insulin analog | Provides a relatively constant level of insulin over 24 hours. |
| Insulin detemir (Levemir) | Long-acting insulin analog | Has a duration of action of up to 24 hours; may require twice-daily dosing. |
| Insulin lispro (Humalog) | Rapid-acting insulin analog | Used to cover meals; faster onset and shorter duration than regular human insulin. |
| Insulin aspart (Novolog) | Rapid-acting insulin analog | Used to cover meals; faster onset and shorter duration than regular human insulin. |
Tresiba Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Hypoglycemia (low blood sugar) | Severe hypoglycemia (can lead to seizures or loss of consciousness) |
| Injection site reactions (redness, pain, swelling) | Allergic reactions (rash, itching, swelling, difficulty breathing) |
| Weight gain | Hypokalemia (low potassium levels) |
Tresiba Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Type 1 Diabetes | Individualized; typically 1/3 to 1/2 of total daily insulin requirement | Individualized; based on blood glucose monitoring and A1C levels | Administer subcutaneously once daily, at any time of day, but preferably at the same time each day. |
| Type 2 Diabetes | 10 units once daily | Individualized; based on blood glucose monitoring and A1C levels | Administer subcutaneously once daily, at any time of day, but preferably at the same time each day. |
Tresiba Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $60 |
| Without Insurance (U.S.) | $335 |
| From Canada | $150 |

