Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
Description
General Medication Fact Sheet for Trexall
| Field | Information |
|---|---|
| Medication Name | Trexall |
| Generic Name | Methotrexate |
| Boxed/Label Warning | Yes. Trexall carries boxed warnings for hepatotoxicity, myelosuppression, gastrointestinal toxicity, pneumonitis, opportunistic infections, dermatologic reactions, malignancy, and embryo-fetal toxicity. |
| Purpose | Disease-modifying antirheumatic drug (DMARD) used to treat rheumatoid arthritis, psoriasis, and certain types of cancer. |
| Mechanism of Action | Inhibits dihydrofolate reductase, an enzyme involved in DNA synthesis, repair, and cellular replication. |
| Dosage Forms | Oral tablets |
| Available Strengths | 2.5 mg, 5 mg, 7.5 mg, 10 mg, 15 mg |
| Dosage Frequency | Typically once weekly for rheumatoid arthritis and psoriasis; dosage varies for cancer treatment. |
| Common Side Effects | Nausea, vomiting, diarrhea, mouth sores, fatigue, hair loss. |
| Serious Side Effects | Liver damage, bone marrow suppression, lung problems, infections, kidney problems, severe skin reactions. |
| Drug Interactions | NSAIDs, certain antibiotics (e.g., trimethoprim/sulfamethoxazole), proton pump inhibitors (PPIs), aspirin, live vaccines. |
| Important Notes | Use effective contraception during treatment and for a period after stopping. Regular monitoring of blood counts and liver function is necessary. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Contact your healthcare provider immediately for instructions. Do not double the dose. |
| Alternatives | Otrexup (methotrexate), Rasuvo (methotrexate), Azathioprine, Leflunomide, Sulfasalazine |
Trexall Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Otrexup (methotrexate) | Inhibits dihydrofolate reductase | Subcutaneous auto-injector form of methotrexate. |
| Rasuvo (methotrexate) | Inhibits dihydrofolate reductase | Subcutaneous auto-injector form of methotrexate. |
| Azathioprine (Imuran) | Purine analog; inhibits DNA and RNA synthesis | Immunosuppressant used in autoimmune conditions. |
| Leflunomide (Arava) | Inhibits pyrimidine synthesis | DMARD for rheumatoid arthritis. |
| Sulfasalazine (Azulfidine) | Mechanism not fully understood; anti-inflammatory properties | Used for rheumatoid arthritis and ulcerative colitis. |
Trexall Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Nausea | Liver damage |
| Vomiting | Bone marrow suppression |
| Diarrhea | Lung problems (pneumonitis, pulmonary fibrosis) |
| Mouth sores | Infections |
| Fatigue | Kidney problems |
| Hair loss | Severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis) |
Trexall Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Rheumatoid Arthritis | 7.5 mg once weekly | 7.5-25 mg once weekly | Administer orally; folic acid supplementation is often recommended. |
| Psoriasis | 10-25 mg once weekly | Individualized based on response and tolerance | Administer orally; folic acid supplementation is often recommended. |
Trexall Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $25 |
| Without Insurance (U.S.) | $1200 |
| From Canada | $500 |
Why Americans Buy Trexall from Canada Pharmacy Store?
Why Americans Buy Trexall from Canada Pharmacy Store?
Americans have trouble affording Trexall due to numerous factors—but at Canada Pharmacy Store, we offer a safe, affordable alternative. That’s why thousands of Americans trust us to fill their prescriptions with real savings and real service.
Big Savings on U.S. Medications
Our customers save up to 80% on their Trexall prescriptions compared to U.S. pharmacy prices by ordering through licensed Canadian and international pharmacies.
Free Prescription Transfers
We make it easy! Our pharmacy team can transfer your Trexall prescriptions directly from your doctor or local pharmacy – completely free of charge.
Direct Access to Experts
Our licensed pharmacists are available to support you, answer your questions, and help ensure you’re confident in your treatment.
Referral Discounts
Spread the word—when you refer friends or family, you both save. It’s our way of saying thanks.
Discreet U.S. Shipping
All orders are packaged discreetly and shipped securely to your U.S. address, with your privacy and safety as top priorities.
Trusted by Americans Nationwide
With years of experience and verified medication sources, we’ve become a go-to solution for Americans looking to cut costs without compromising care.
How to Order Trexall Online
How to Order Trexall Online
Step 1
Select Your Prescribed Trexall Dosage
Choose the strength and quantity as directed by your healthcare provider and add it to your cart.
Step 2
Proceed Through Secure Checkout
Follow the steps to complete your order and provide necessary shipping and payment details.
Step 3
Upload Your Trexall Prescription
Submit a prescription from a licensed U.S. healthcare provider that matches your order.
At Canada Pharmacy Store, patient safety comes first. We strictly comply with prescription regulations and do not ship any medication without a valid, verifiable prescription. Orders may be declined if a prescription appears falsified or altered in any way. We take these precautions to protect your health and ensure lawful, responsible practices.
Guarantee
Our Guarantee When You Buy Trexall Through Canada Pharmacy Store
At Canada Pharmacy Store, your safety and satisfaction are our top priorities. We supply only authentic, high-quality medications by working exclusively with licensed Canadian pharmacies and trusted international partners. Every order is filled in accordance with strict regulatory standards and includes medication that’s fully approved by Health Canada or other recognized health authorities such as the MHRA (UK), HSA (Singapore), and the Pharmacy Board of Mauritius.
The Trexall you receive is the same active medication as what’s available in the U.S.—the only difference is the packaging, which reflects its country of origin. Our licensed healthcare professionals review each order carefully to ensure it matches your prescription exactly.
To get Trexall at a lower price, simply place your order above or give us a call at 1-888-903-2240
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