Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
Description
General Medication Fact Sheet for Treximet
| Field | Information |
|---|---|
| Medication Name | Treximet |
| Generic Name | Sumatriptan and Naproxen Sodium |
| Boxed/Label Warning | NSAIDs like Naproxen, a component of Treximet, increase the risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. This risk may occur early in treatment and may increase with duration of use. Treximet is contraindicated in the setting of coronary artery bypass graft (CABG) surgery. NSAIDs like Naproxen, a component of Treximet, increase the risk of serious gastrointestinal (GI) adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. These events can occur at any time during use and without warning symptoms. Elderly patients and patients with a prior history of peptic ulcer disease and/or GI bleeding are at greater risk for serious GI events. |
| Purpose | Acute treatment of migraine attacks with or without aura in adults. |
| Mechanism of Action | Combines a selective 5-HT1B/1D receptor agonist (Sumatriptan) and a nonsteroidal anti-inflammatory drug (Naproxen sodium). Sumatriptan constricts cranial blood vessels and inhibits the release of pro-inflammatory neuropeptides. Naproxen inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin synthesis, thereby reducing inflammation and pain. |
| Dosage Forms | Oral tablets |
| Available Strengths | Sumatriptan 85 mg / Naproxen Sodium 500 mg |
| Dosage Frequency | A single tablet is to be taken as soon as symptoms of migraine occur. Do not take more than 2 tablets in 24 hours. |
| Common Side Effects | Dizziness, nausea, somnolence, chest pain, muscle tightness, neck pain or stiffness. |
| Serious Side Effects | Heart attack, stroke, serious gastrointestinal bleeding, liver damage, severe allergic reactions. |
| Drug Interactions | Other triptans, ergot-containing medications, MAO inhibitors, SSRIs, SNRIs, other NSAIDs, anticoagulants, aspirin. |
| Important Notes | Use with caution in patients with cardiovascular risk factors. Not for prophylactic use. Report any signs of bleeding or allergic reaction immediately. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Treximet is used as needed for acute migraine attacks. It is not intended for daily use. |
| Alternatives | Sumatriptan, Naproxen, Ibuprofen, Rizatriptan |
Treximet Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Sumatriptan (Imitrex) | Selective 5-HT1B/1D receptor agonist | Used for acute migraine relief by constricting blood vessels and reducing inflammation. |
| Naproxen (Aleve) | Non-selective COX inhibitor | NSAID used for pain and inflammation. Available over-the-counter. |
| Ibuprofen (Advil, Motrin) | Non-selective COX inhibitor | NSAID used for pain and inflammation. Available over-the-counter. |
| Rizatriptan (Maxalt) | Selective 5-HT1B/1D receptor agonist | Another triptan medication for migraine relief. May be faster acting for some individuals. |
Treximet Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Dizziness | Heart attack |
| Nausea | Stroke |
| Somnolence | Gastrointestinal bleeding |
| Chest pain | Liver damage |
| Muscle tightness | Severe allergic reactions (anaphylaxis) |
| Neck pain or stiffness | Seizures |
Treximet Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Migraine | 1 tablet (Sumatriptan 85mg / Naproxen Sodium 500mg) | N/A (Single dose for acute migraine) | Take at the onset of migraine symptoms. Do not exceed 2 tablets in 24 hours. |
Treximet Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $100 |
| Without Insurance (U.S.) | $1540 |
| From Canada | $98 |
Why Americans Buy Treximet from Canada Pharmacy Store?
Why Americans Buy Treximet from Canada Pharmacy Store?
Americans have trouble affording Treximet due to numerous factors—but at Canada Pharmacy Store, we offer a safe, affordable alternative. That’s why thousands of Americans trust us to fill their prescriptions with real savings and real service.
Big Savings on U.S. Medications
Our customers save up to 80% on their Treximet prescriptions compared to U.S. pharmacy prices by ordering through licensed Canadian and international pharmacies.
Free Prescription Transfers
We make it easy! Our pharmacy team can transfer your Treximet prescriptions directly from your doctor or local pharmacy – completely free of charge.
Direct Access to Experts
Our licensed pharmacists are available to support you, answer your questions, and help ensure you’re confident in your treatment.
Referral Discounts
Spread the word—when you refer friends or family, you both save. It’s our way of saying thanks.
Discreet U.S. Shipping
All orders are packaged discreetly and shipped securely to your U.S. address, with your privacy and safety as top priorities.
Trusted by Americans Nationwide
With years of experience and verified medication sources, we’ve become a go-to solution for Americans looking to cut costs without compromising care.
How to Order Treximet Online
How to Order Treximet Online
Step 1
Select Your Prescribed Treximet Dosage
Choose the strength and quantity as directed by your healthcare provider and add it to your cart.
Step 2
Proceed Through Secure Checkout
Follow the steps to complete your order and provide necessary shipping and payment details.
Step 3
Upload Your Treximet Prescription
Submit a prescription from a licensed U.S. healthcare provider that matches your order.
At Canada Pharmacy Store, patient safety comes first. We strictly comply with prescription regulations and do not ship any medication without a valid, verifiable prescription. Orders may be declined if a prescription appears falsified or altered in any way. We take these precautions to protect your health and ensure lawful, responsible practices.
Guarantee
Our Guarantee When You Buy Treximet Through Canada Pharmacy Store
At Canada Pharmacy Store, your safety and satisfaction are our top priorities. We supply only authentic, high-quality medications by working exclusively with licensed Canadian pharmacies and trusted international partners. Every order is filled in accordance with strict regulatory standards and includes medication that’s fully approved by Health Canada or other recognized health authorities such as the MHRA (UK), HSA (Singapore), and the Pharmacy Board of Mauritius.
The Treximet you receive is the same active medication as what’s available in the U.S.—the only difference is the packaging, which reflects its country of origin. Our licensed healthcare professionals review each order carefully to ensure it matches your prescription exactly.
To get Treximet at a lower price, simply place your order above or give us a call at 1-888-903-2240
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