Notice: Images are for illustration only and may not reflect the exact product you receive. Brand-name medications may look different depending on their country of origin—Canadian versions, for example, often include a "PR" symbol on the packaging. Rest assured, the medication, dosage, and active ingredients will be exactly as prescribed. Canada Pharmacy Store is committed to your health and safety, and we work only with licensed pharmacies to ensure you receive trusted, high-quality medication every time.
Description
General Medication Fact Sheet for Trifexis
| Field | Information |
|---|---|
| Medication Name | Trifexis |
| Generic Name | Milbemycin oxime/spinosad |
| Purpose | Prevents heartworm disease, kills adult fleas, and treats and controls adult hookworm, roundworm, and whipworm infections in dogs. |
| Mechanism of Action | Milbemycin oxime interferes with parasite nerve transmission. Spinosad causes uncontrolled neuromuscular excitation in fleas and other insects. |
| Dosage Forms | Oral chewable tablets |
| Available Strengths | Vary based on dog’s weight (e.g., 5-10 lbs, 10.1-20 lbs, 20.1-40 lbs, 40.1-60 lbs, 60.1-120 lbs) |
| Dosage Frequency | Once a month |
| Common Side Effects | Vomiting, diarrhea, lethargy, decreased appetite, itching |
| Serious Side Effects | Seizures, incoordination, hypersensitivity reactions (hives, facial swelling, difficulty breathing) |
| Drug Interactions | Other medications that can cause neurological effects (consult with veterinarian). |
| Important Notes | Administer with food for better absorption. Consult with veterinarian before use in dogs with a history of seizures. |
| Storage | Store at room temperature, away from moisture and direct sunlight. |
| Missed Dose | Give the missed dose immediately and resume monthly dosing schedule. |
| Alternatives | Heartgard Plus (ivermectin/pyrantel), Interceptor Plus (milbemycin oxime/praziquantel), Revolution (selamectin), Advantage Multi (imidacloprid/moxidectin) |
Trifexis Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Heartgard Plus (ivermectin/pyrantel) | Ivermectin: Interferes with parasite nerve and muscle function; Pyrantel: Acts as a depolarizing neuromuscular blocking agent. | Prevents heartworm and treats certain intestinal worms. Does not treat fleas. |
| Interceptor Plus (milbemycin oxime/praziquantel) | Milbemycin oxime: Interferes with parasite nerve transmission; Praziquantel: Increases cell membrane permeability in the parasite. | Prevents heartworm and treats/controls various intestinal worms. Does not treat fleas. |
| Revolution (selamectin) | Selamectin: Interferes with nerve and muscle function in parasites. | Prevents heartworm, kills adult fleas, treats ear mites and sarcoptic mange, and controls certain ticks and worms. |
| Advantage Multi (imidacloprid/moxidectin) | Imidacloprid: Blocks nerve transmission in fleas; Moxidectin: Interferes with parasite nerve transmission. | Prevents heartworm, kills adult fleas, and treats certain intestinal worms and mites. |
Trifexis Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Vomiting | Seizures |
| Diarrhea | Incoordination |
| Lethargy | Hypersensitivity reactions (hives, facial swelling, difficulty breathing) |
| Decreased appetite | Collapse |
| Itching | Neurologic signs |
Trifexis Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Heartworm Prevention, Flea and Intestinal Worm Treatment | Based on dog’s weight (see product label) | Continue monthly dosing based on dog’s weight. | Administer orally, preferably with food. Use appropriate strength based on dog’s weight. Consult veterinarian for specific dosing. |
Trifexis Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $160 |
| Without Insurance (U.S.) | $40 |
| From Canada | $123 |
Why Americans Buy Trifexis from Canada Pharmacy Store?
Why Americans Buy Trifexis from Canada Pharmacy Store?
Americans have trouble affording Trifexis due to numerous factors—but at Canada Pharmacy Store, we offer a safe, affordable alternative. That’s why thousands of Americans trust us to fill their prescriptions with real savings and real service.
Big Savings on U.S. Medications
Our customers save up to 80% on their Trifexis prescriptions compared to U.S. pharmacy prices by ordering through licensed Canadian and international pharmacies.
Free Prescription Transfers
We make it easy! Our pharmacy team can transfer your Trifexis prescriptions directly from your doctor or local pharmacy – completely free of charge.
Direct Access to Experts
Our licensed pharmacists are available to support you, answer your questions, and help ensure you’re confident in your treatment.
Referral Discounts
Spread the word—when you refer friends or family, you both save. It’s our way of saying thanks.
Discreet U.S. Shipping
All orders are packaged discreetly and shipped securely to your U.S. address, with your privacy and safety as top priorities.
Trusted by Americans Nationwide
With years of experience and verified medication sources, we’ve become a go-to solution for Americans looking to cut costs without compromising care.
How to Order Trifexis Online
How to Order Trifexis Online
Step 1
Select Your Prescribed Trifexis Dosage
Choose the strength and quantity as directed by your healthcare provider and add it to your cart.
Step 2
Proceed Through Secure Checkout
Follow the steps to complete your order and provide necessary shipping and payment details.
Step 3
Upload Your Trifexis Prescription
Submit a prescription from a licensed U.S. healthcare provider that matches your order.
At Canada Pharmacy Store, patient safety comes first. We strictly comply with prescription regulations and do not ship any medication without a valid, verifiable prescription. Orders may be declined if a prescription appears falsified or altered in any way. We take these precautions to protect your health and ensure lawful, responsible practices.
Guarantee
Our Guarantee When You Buy Trifexis Through Canada Pharmacy Store
At Canada Pharmacy Store, your safety and satisfaction are our top priorities. We supply only authentic, high-quality medications by working exclusively with licensed Canadian pharmacies and trusted international partners. Every order is filled in accordance with strict regulatory standards and includes medication that’s fully approved by Health Canada or other recognized health authorities such as the MHRA (UK), HSA (Singapore), and the Pharmacy Board of Mauritius.
The Trifexis you receive is the same active medication as what’s available in the U.S.—the only difference is the packaging, which reflects its country of origin. Our licensed healthcare professionals review each order carefully to ensure it matches your prescription exactly.
To get Trifexis at a lower price, simply place your order above or give us a call at 1-888-903-2240
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