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General Medication Fact Sheet for Trilipix
| Field | Information |
|---|---|
| Medication Name | Trilipix |
| Generic Name | Fenofibric Acid |
| Purpose | Used to lower triglycerides and increase HDL cholesterol (good cholesterol) in the blood. |
| Mechanism of Action | Activates peroxisome proliferator-activated receptor alpha (PPARα), increasing lipolysis and reducing triglyceride synthesis. |
| Dosage Forms | Delayed-release capsules |
| Available Strengths | 45 mg, 135 mg |
| Dosage Frequency | Once daily |
| Common Side Effects | Headache, muscle pain, nausea, runny nose |
| Serious Side Effects | Liver problems, muscle damage (rhabdomyolysis), pancreatitis, blood clots |
| Drug Interactions | Statins (e.g., atorvastatin, simvastatin), anticoagulants (e.g., warfarin), bile acid sequestrants (e.g., cholestyramine) |
| Important Notes | Take with food; monitor liver function and cholesterol levels regularly; report any unexplained muscle pain or weakness to your doctor. |
| Storage | Store at room temperature away from moisture and light. |
| Missed Dose | Take as soon as you remember; skip if it’s almost time for your next dose. Do not double the dose. |
| Alternatives | Fenofibrate (Tricor, Antara, Lofibra), Gemfibrozil (Lopid), Lovaza (Omega-3 Acid Ethyl Esters) |
Trilipix Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Fenofibrate (Tricor, Antara, Lofibra) | Activates PPARα, increasing lipolysis and reducing triglyceride synthesis. | A similar fibric acid derivative, available in various formulations. |
| Gemfibrozil (Lopid) | Activates PPARα, increasing lipolysis and reducing triglyceride synthesis. | Another fibric acid derivative, but with a different chemical structure than fenofibric acid or Fenofibrate. |
| Lovaza (Omega-3 Acid Ethyl Esters) | Reduces hepatic triglyceride synthesis and increases triglyceride clearance. | Contains omega-3 fatty acids; primarily lowers triglycerides. |
| Niacin (Niaspan) | Inhibits lipolysis in adipose tissue and reduces hepatic VLDL synthesis. | Can raise HDL cholesterol more effectively than fibrates, but has more side effects. |
Trilipix Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Headache | Liver problems (increased liver enzymes) |
| Muscle pain | Muscle damage (rhabdomyolysis) |
| Nausea | Pancreatitis |
| Runny nose | Blood clots (pulmonary embolism, deep vein thrombosis) |
| Back pain | Allergic reactions (rash, itching, swelling) |
Trilipix Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| Hypertriglyceridemia (High Triglycerides) | 45 mg or 135 mg | 45 mg or 135 mg once daily | Take with food. Dosage depends on individual needs and response. |
| Mixed Dyslipidemia (High Triglycerides and Low HDL) | 45 mg or 135 mg | 45 mg or 135 mg once daily | Take with food. Dosage depends on individual needs and response. |
