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General Medication Fact Sheet for Triumeq
| Field | Information |
|---|---|
| Medication Name | Triumeq |
| Generic Name | Abacavir, Dolutegravir, Lamivudine |
| Boxed/Label Warning | Serious hypersensitivity reactions and exacerbation of hepatitis B. |
| Purpose | Treatment of HIV-1 infection |
| Mechanism of Action | Inhibits HIV-1 reverse transcriptase and integrase enzymes, blocking viral replication. |
| Dosage Forms | Oral tablets |
| Available Strengths | 600 mg abacavir / 50 mg dolutegravir / 300 mg lamivudine |
| Dosage Frequency | Once daily |
| Common Side Effects | Insomnia, headache, fatigue, diarrhea, nausea |
| Serious Side Effects | Hypersensitivity reactions, liver problems, lactic acidosis, immune reconstitution syndrome |
| Drug Interactions | Certain antacids, metformin, rifampin, other antiretroviral medications |
| Important Notes | Do not take with other medications containing abacavir or lamivudine. Test for HLA-B*5701 allele before starting therapy. |
| Storage | Store at room temperature away from moisture and light |
| Missed Dose | Take as soon as you remember; if it is almost time for your next dose, skip the missed dose and take your next dose at the regular time. Do not double the dose. |
| Alternatives | Dovato (dolutegravir/lamivudine), Biktarvy (bictegravir/emtricitabine/tenofovir alafenamide), Odefsey (emtricitabine/rilpivirine/tenofovir alafenamide) |
Triumeq Alternatives
| Medication | Mechanism of Action | Notes |
|---|---|---|
| Dovato (dolutegravir/lamivudine) | Integrase strand transfer inhibitor (INSTI) + Nucleoside reverse transcriptase inhibitor (NRTI) | Two-drug regimen; suitable for some patients with HIV-1 |
| Biktarvy (bictegravir/emtricitabine/tenofovir alafenamide) | INSTI + NRTI combination | Commonly prescribed single-tablet regimen |
| Odefsey (emtricitabine/rilpivirine/tenofovir alafenamide) | NRTI + Non-nucleoside reverse transcriptase inhibitor (NNRTI) | Requires low viral load and no known resistance to rilpivirine |
Triumeq Side Effects
| Common Side Effects | Serious Side Effects |
|---|---|
| Insomnia | Hypersensitivity reactions (fever, rash, fatigue, GI symptoms, respiratory symptoms) |
| Headache | Liver problems (hepatotoxicity) |
| Fatigue | Lactic acidosis (weakness, tiredness, muscle pain, trouble breathing, stomach pain with nausea, vomiting) |
| Diarrhea | Immune reconstitution syndrome (inflammatory response to opportunistic infections) |
| Nausea | Depression or mood changes |
Triumeq Dosage Guide
| Condition | Starting Dose | Maintenance Dose | Administration Notes |
|---|---|---|---|
| HIV-1 Infection | One tablet daily | One tablet daily | Take once daily with or without food. |
Triumeq Price With And Without Insurance
| Purchase Context | Estimated Price |
|---|---|
| With Insurance | $50 |
| Without Insurance (U.S.) | $4000 |
| From CPS | $1512 |
